Turkish Neurosurgery 2017 , Vol 27 , Num 1
Surgical Outcome of Endoscopic Endonasal Surgery for Non-Functional Pituitary Adenoma by a Team of Neurosurgeons and Otolaryngologists Adenoma by a Team of Neurosurgeons and Otolaryngologists
Ryogo KIKUCHI1,Masahiro TODA1,Toshiki TOMITA2,Kaoru OGAWA2,Kazunari YOSHIDA1
1Keio University School of Medicine, Department of Neurosurgery, Shinjuku, Tokyo, Japan
2Keio University School of Medicine, Departments of Otorhinolaryngology, Head & Neck Surgery, Shinjuku, Tokyo, Japan
DOI : 10.5137/1019-5149.JTN.14354-15.0 AIM: This study aimed to assess the efficacy of endoscopic endonasal surgery, conducted by a team of neurosurgeons and otolaryngologists.

MATERIAL and METHODS: We studied 40 patients who were undergoing surgery for primary non-functional pituitary adenomas with Knosp grades 1 to 3, at Keio University Hospital between 2005 and 2012. We compared the endoscopic endonasal transsphenoidal approach (team-eTSS; T-eTSS), with a microscopic transsphenoidal approach (mTSS). Analyses were conducted for differences between the two groups in tumor resection rates, operating durations, and complications from the non-functional pituitary adenomas. We also compared the heminostril and binostril approaches for T-eTSS.

RESULTS: Tumor resection rates were higher when the surgeries were conducted by T-eTSS than mTSS. In particular, when the maximum tumor diameter was more than 25 mm, resection rates were significantly higher for T-eTSS than for mTSS. There were no unexpected complications in either group. There was no significant difference in resection rates between the heminostril and binostril approaches when T-eTSS was performed.

CONCLUSION: T-eTSS is an efficacious surgical option for non-functional pituitary adenomas, particularly when the adenoma is of large size. Benefits of the heminostril approach are evident. Keywords : Endoscopic endonasal surgery, Pituitary adenoma, Heminostril approach, Transsphenoidal