|Congenital glioblastoma: lessons learned from a rare case with unusual presentation.|
|Atef Ben Nsir1, Mehdi Darmoul1, Rym Hadhri2, Nejib Hattab1|
|1Fattouma Bourguiba University Hosital, Neurosurgery Department, Monastir,
2Fattouma Bourguiba University Hosital, Pathology Department, Monastir,
Congenital glioblastomas are uncommon tumors of infancy with unique molecular features and usually better prognosis compared to their pediatric and adult counterparts. A 15-day old newborn harboring a congenital glioblastoma undiagnosed at pregnancy presented to our emergencies with rapid neurological deterioration. Radiological investigations revealed an 8 by 9 cm space occupying and enhancing lesion in the left temporoparietooccipital region with intratumoral hemorrhage. The patient was immediately transferred to the operative theater and was operated in a poor condition. Unfortunately he showed no improvement post-operatively and died within two days in the intensive care unit. As such presentation is unique; we present the case and review the relevant literature concerning the potential pitfalls in diagnosis, management strategies and improvements in outcome.
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