Turkish Neurosurgery
Massive Skull Base Ameloblastic Carcinoma with Intracranial Extension
Ali Erdem Yildirim1, Denizhan Divanlioglu1, Derya Karaoglu1, Serra Kayacetin 2, Ahmed Deniz Belen1
1Ankara Numune Research and Education Hospital, Neurosurgery, Ankara,
2Ankara Numune Research and Education Hospita, Pathology, ANKARA,
DOI: 10.5137/1019-5149.JTN.14101-15.3

Ameloblastic carcinoma (AC) is a rare and aggressive malignant epithelial odontogenic tumor which may arise either from the mandibula (66.6%) or the maxilla (33. %3). Besides being formed de novo the tumor can develop from a pre-existing ameloblastoma or odontogenic cyst. The clinical course of AC is typically aggressive with extensive local destruction. AC has also been reported to spread to various parts of the body through lymphatic system. Skull base location and intracranial extension of this tumor are uncommon. In this case report we present the clinical course, management and follow up of an uncommonly large AC which destructed anterior skull base and extended into the intracranial space.

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