Turkish Neurosurgery
The Relationship of Hematoma Growth to RDW in Patients with Hypertensive Intracerebral Hemorrhage
Özge Altıntaş1, Hümeyra Dürüyen2, Gözde Baran2, Oğuz Baran3, Salim Katar3, Veysel Antar3, Talip Asil4
1Bor State Hospital, Neurology Clinic, Nigde,
2Sisli Hamidiye Etfal Research and Training Hospital, Neurology Clinic, İstanbul,
3Istanbul Research and Training Hospital, Neurosurgery Clinic, İstanbul,
4Bezmialem Vakif University Medical Faculty, Department of Neurology, İstanbul,
DOI: 10.5137/1019-5149.JTN.16136-15.1

Aim:Hypertension is a primary risk factor for intracerebral hemorrhage (ICH) and is thought to be responsible for about 55% of all ICH cases. Thus, the primary goal of the study was to examine whether the status of vascular rheological factors upon admission to the hospital was associated with hypertensive ICH growth and early outcomes. Material and Methods:Over a 2-year period, the present study evaluated 60 ICH patients who were admitted within the first 12 hours of symptom onset. Brain computed tomography scans were performed at admission and then 24 hours later as a control. Hematoma growth was classified as an increase > 6.5 ml or > 33% and good outcomes were defined using the modified Rankin Scale (mRS) score (≤ 2 at 3 months).Results:The leading vascular risk factor was hypertension (86.7%) .There were significant associations between the initial platelet distribution width (PDW) and a mRS score of 0-2 at 3 months (p = 0.047) and between the initial red blood cell distribution width (RDW) and hematoma growth (p = 0.038). Therefore, hematoma growth in the first 24 hours after symptom onset was significantly related to a poor clinical outcome at 3 months (p = 0.050).Conclusion:The study identified significant relationships between the initial PDW and behavioral outcomes as well as the initial RDW and hypertensive hematoma growth. Additionally, this study demonstrated these parameters are easily obtainable and could be used to effectively evaluate outcomes in ICH patients.

Corresponding author : Oğuz Baran