Aim:Fusion development is the primary objective in spinal surgeries that are conducted for the treatment of vertebra corpus related pathologies such as trauma, tumor and infection. Stabilization using metal plate screws together either with autograft, allograft or xenografts methods are used. Fusion development in stabilizations that are carried out with xenograft (XG) with XG plate-screw (XPS) and XG with metal plate-screw (MPS) systems in dogs’ lumbar vertebra (L5-7 segment) was examined in terms of radiology, biomechanics and histopathologic aspects.Material and Methods:The subjects were separated into 4 groups each includes 5 subjects. The experiment consisted of control group 1, which did not go through any procedure and is stabilized, control group 2 which go through instability with only L6 anterior corpectomy, experimental group 1, which was stabilized with intervertebral XG and XPS after L6 corpectomy, experimental group 2 that was stabilized with intervertebral XG and MPS after L6 corpectomy. Fusion generation in the experimental group 1 and 2 was examined in terms of radiologic and histopathologic aspects. Results:Comparison of control and experimental groups resulted with an increase in resistance in all activities in biomechanical tests (p<0.01). Fusion development was observed in the radiological and histopathologic examinations of the subjects in the experimental group. On the other hand experimental group 1 and 2 did not show significant difference in the biomechanical test comparisons (p>0.05).Conclusion:Our study revealed that xenograft plate screw and metal plate screws provided equivalent fusion and stabilization in anterior lumbar stabilization.