Turkish Neurosurgery
Retrospective Analysis of 449 Intracranial Meningioma Patients Operated between years 2007 – 2013 in a Single Institute
Emrah Celtikci3, A. Memduh Kaymaz1, Gulsah Akgul4, Burak Karaaslan1, O. Hakan Emmez1, Alp Borcek2
1Gazi University Faculty of Medicine, Neurosurgery, Ankara,
2Gazi University Faculty of Medicine, Neurosurgery, Div of Pediatric Neurosurgery, Ankara,
3Yildirim Beyazit University, Yenimahalle R&E Hospital, Neurosurgery, Ankara,
4Yuksek Ihtisas University, Pathology, Ankara,
DOI: 10.5137/1019-5149.JTN.17866-16.1

Aim:Meningioma literature has many large surgical case series which have been references of text books and neurosurgical practice. Many of those series were investigated before stereotactic radiosurgery (SRS) practice were not so often or were in terms of WHO 2000 classification. In this study we aimed an update to the current literature by using WHO 2007 classification.Material and Methods:488 intracranial meningioma patients underwent open surgery. All pathological specimens re-evaluated in terms of WHO 2007 classification. All demographical and follow up records and imaging archives were investigated by using our center’s central automation system and National Central Population Management System. If records were not available or not enough, investigators made phone calls to patients. Pediatric patients excluded.Results:326 female (76,2%) and 123 male (27,4%) patients analysed and were 18 to 84 years old (51,6 ± 11,9). Most common subtype is meningothelial meningioma (n = 232, 51,7%), following by atypical subtype (n = 91, 20,3%). Also WHO Grade I meningiomas has statistically random localization distribution but WHO Grade II meningiomas are more common in convexity, parasagittal and middle fossa. Younger patient age was found significantly related with recurrence or progression. 73 (16,2%) patients underwent SRS and 64 (14,2%) patients underwent adjuvant radiotherapy (ART) after surgery. Convexity localization was found to be associated with recurrence, mortality and higher WHO 2007 grade.Conclusion:Meningiomas located in the convexity are associated with recurrence, mortality and higher WHO 2007 grade. To achieve maximum benefit from surgery, meningiomas of this localization should be totally resected.

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