Aim:The purpose of the current study is to present our experience of awake craniotomy (AC) method, starting from the preoperative period, to report the morbidity and the functional outcomes along with the complications in patients who underwent AC, and to make recommendations for possible problems. Material and Methods:This study involved 46 cases- 2 of which are pediatric cases with lesions localized in the functional area- who were operated with AC method between September 2011 and January 2016 in our clinic. The age range of the cases was 12 and 81. The average age was 48. Both preoperative and postoperative (month 1, 3, 6 and 12) neurological examinations were recorded. Results:Of 46 patients who had AC surgery in this series, 17 were observed to have worsening neurological deterioration in intraoperative period. On month 1 follow-up, 13 of these 17 patients were observed to have a full neurological recovery. Moreover, 4 patients that developed hemiplegia were able to mobilized with support on month 6 follow-up. All patients were observed to have a return of language to baseline preoperative function on month 1 follow-up.Conclusion:When the results of the AC method were examined, it was observed that the rates of persistent postoperative neurological deficit rates were very low in the follow-up period. Based on our practice presented here, it could be concluded that the precise synchrony among the surgeon, the anesthesia team and the patient is a must for AC to be successful and for the preservation of language and motor functions.