Turkish Neurosurgery
Spinal peripheral primitive neuroectodermal tumors: A radiological study of ten cases
xiaoping yi1, moling zhou1, shenghui liao3, guanghui gong4, hongling yin4, yongheng chen5, weihua liao1
1Xiangya Hospital, Central South University, radiology, changsha,
2Basic Medical Sciences, Xiangya Hospital,Central South University,, Postdoctoral Research Workstation of Pathology and Pathophysiology, changsha,
3Central South University,, School of Information Science and Engineering, changsha ,
4Xiangya Hospital, Central South University, Pathology, changsha,
5Xiangya Hospital, Central South University, Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, changsha,
DOI: 10.5137/1019-5149.JTN.21931-17.2

Aim:To summarize the imaging features of spinal peripheral primitive neuroectodermal tumor (spPNET) patients.Material and Methods:The computed tomography (CT) and magnetic resonance imaging (MRI) features of ten spPNET patients were retrospectively analyzed, and the clinicopathological data were reviewed.Results:Four men and six women with a mean age of 24.7 years (range, 3-44 years) were included. A total of ten spPNET lesions were found in the ten patients, including six extradural and four intradural extramedullary lesions. Radiologically, spPNET usually presented as heterogeneous iso-intense lesions with a heterogeneously enhanced pattern. A “vault wall-like growth” pattern, a linear enhancement pattern, and vertebral bone involvement tended to be found in extradural lesions, and a ring enhancement pattern was found in extramedullary intradural lesions. Positive Ki-67 expression might be related to necrosis, bone destruction, and hemorrhage.Conclusion:A well-defined spinal mass showing iso-intensity/attenuation with heterogeneous enhancement accompanied by other imaging features may be suggestive of spPNET and should be added to the list of differential diagnosis symptoms.

Corresponding author : xiaoping yi