Turkish Neurosurgery
Systematic Evaluation of Desmopressin Applied to the Patients with Aneurysmal Subarachnoid Haemorrhage in the light of the Literature
Numan KARAARSLAN1, Ibrahim YILMAZ2, Feride Sinem AKGUN3, Tezcan CALISKAN1, Hanefi OZBEK2, Ozkan ATES4
1Namık Kemal University Scholl of Medicine , Neurosurgery , Tekirdağ,
2Istanbul Medipol University School of Medicine, Medical Pharmacology, Istanbul,
3Istanbul Maltepe University School of Medicine, Emergency Medicine, Istanbul,
4Istanbul Esenyurt University, Esencan Hospital, Neurosurgery , Istanbul,
DOI: 10.5137/1019-5149.JTN.23064-18.1

Aim:This study discusses the management of patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH), developed after subarachnoid hemorrhage, in a comparative manner in light of the literature.Material and Methods:Without country or language restrictions, articles with high evidential value found in electronic databases were compared to our patients’ data.Results:After the literature review, three articles were included for systematic evaluation. Desmopressin was applied to the patients for the treatment of hyponatremia, volume contraction, and negative sodium balance caused by SIADH. However, it was not used for preventing re-bleeding.Conclusion:To prevent the development of this complication (SIADH), the use of desmopressin, an analogue of vasopressin, is important in routine clinical practice.

Corresponding author : Numan KARAARSLAN