Turkish Neurosurgery
Clinical Study of Ultrasound-Guided Methylene Blue Thoracic Paravertebral Nerve Block for the Treatment of Postherpetic Neuralgia
Ping ZHAO1, Lisha MEI1, Weizhi WANG1
1Weifang People\'s Hospital, Department of Anesthesiology, Weifang ,
DOI: 10.5137/1019-5149.JTN.24950-18.2

Aim:The aim of this study was to investigate the effect of ultrasound-guided methylene blue (MB) thoracic paravertebral nerve block (TPVB) on the treatment of postherpetic neuralgia (PHN).Material and Methods:A total of 27 patients with PHN were treated with ultrasound-guided TPVB in the lesion innervation. The blocking drug used was an MB compound preparation, and several indexes were recorded, including pain visual analogue scores (VAS), dosage of oral analgesic required, plasma interleukin (IL)-6, tumor necrosis factor-alpha (TNF-α), and cortisol levels, basic viability, self-assessment, and satisfaction.Results:The patients’ VAS after blocking were significantly reduced compared to those before blocking. Furthermore, dosage of oral analgesic required, levels of plasma IL-6, TNF-α, and cortisol were reduced, and basic viability and self-assessments were significantly improved (P < 0.05). The treatment method was effective, did not cause any adverse effects, and patients reported higher degrees of satisfaction.Conclusion:Ultrasound-guided TPVB exerts significant effects on PHN. The patients’ degree of pain and dosage of oral analgesic required were reduced, basic patient viability was improved, and patients reported higher degrees of satisfaction.

Corresponding author : Weizhi WANG