Turkish Neurosurgery
Treatment of cavernous sinus hemangiomas with Gamma Knife Radiosurgery as a primary and sole therapy
ozgur kardes1, kadir tufan1
1Baskent University, Neurosurgey, Adana,
DOI: 10.5137/1019-5149.JTN.25564-18.1

Aim:The aim of current study is, to evaluate the effectiveness of Gamma Knife Radiosurgery (GKS) as a primary and sole therapy for the treatment of cavernous sinus hemangiomas (CSH) and to report the tumor volume dynamics, course of symptoms and complications after SRS.Material and Methods:A total of 10 CSH patientswere treated with GKS with amedian margin dose of 14.2Gy (range 13-16Gy). The median follow-up was 42 months (range, 12-85 months). Tumor volumes were calculated from magnetic resonance images before the treatment, and compared with the tumor volumes after the treatment.Results:All patients have complained of headache and retroorbital pain and 6 patients have complained of diplopia due to abducens nerve paralysis before the treatment. All patients declared some improvement for their previous headache and retroorbital pain and abducens nerve palsy was fully recovered in all 6 patients, within 6 months after the treatment. At the first year follow-up, at least 74% of volume decrease was noted and average tumor volume reduction was 90.2% among the treated patients. Tumors less than 6 cm3 volume were nearly disappeared at 24 months. There was no tumor progression, re-growth or radiation induced adverse effect in our series.Conclusion:Due to characteristic radiological findings of CSH, there is no need to open biopsy for diagnosis. In appropriate cases, GKSmay be considered as a primary and sole therapy for CSH. Gamma Knife has favorable outcomes for the treatment of CSH with good tumor shrinkage, symptom recovery and acceptable low side effects.

Corresponding author : ozgur kardes