Aim:Recurrence after lumbar disc operation is frequently encountered during daily practice. Full-endoscopic discectomy is an alternative method for revision surgery which causes less intraoperative complications when compared to microdiscectomy procedures. The purpose of this study is to determine the feasibility and effectiveness of full endoscopic discectomy for recurrent disc herniation.Material and Methods:60 patients were investigated in this retrospective single-center study. 36 patients with a history of previous microdiscectomy, underwent revisional full-endoscopic interlaminar discectomy (FEID) (microscopic group); whereas 24 patients with a history of previous FEID had a revisional FEID (endoscopic group). In addition to general parameters, the following measuring tests were used: Visual Analog Scale (VAS) and Oswestry Low-Back Pain Disability (ODI) questionnaire. Results:The mean follow-up period was 36 months. There were no statistically significant difference of hospitalization length, time to return to work, complications and recurrences between two groups. Both endoscopic and microscopic groups revealed significant decrease in the postoperative VAS and ODI scores. The mean operation time was shorter in the endoscopic group compared to the microscopic group which showed statistically significant difference (P < 0.05). At the 36-month follow-up postoperatively, there were no significant differences of postoperative VAS and ODI scores between the two groups. There were no complications related to surgery. Three patients with previous microdiscectomy or endoscopic discectomy had recurrence despite revisional endoscopic surgeryConclusion:Percutaneous full-endoscopic revisional lumbar disc surgery is a safe and effective procedure without additional structural damage. Full endoscopic technique can be used safely for recurrent disc herniations whether operated microscopically or endoscopically.