Turkish Neurosurgery
Effect of Antithrombotic Therapy on Development of Acute Subdural Hematoma After Burr Hole Drainage of Chronic Subdural Hematoma
Mehmet Onur Yüksel1, Serdar Çevik2, Barış Erdoğan3, Tamer Tunçkale4, Salim Katar5, Semra Işık6, Tezcan Çalışkan4, Şevket Evran7
1Medipol University, Neurosurgery, Istanbul,
2Memorial Şişli Hospital, Neurosurgery, Istanbul,
3Şanlıurfa Training and Research Hospital, Neurosurgery, Sanliurfa,
4Tekirdağ Namık Kemal University, Neurosurgery, Tekirdağ,
5Balıkesir University, Neurosurgery, Balıkesir,
6Başkent University, Neurosurgery, Istanbul,
7Haseki Training and Research Hospital, Neurosurgery, Istanbul,
DOI: 10.5137/1019-5149.JTN.30423-20.3

Aim:To evaluate the relationship between the time from termination of anticoagulant/antiplatelet medication to surgery and the risk of acute postoperative hemorrhage in CSDH patients.Material and Methods:A retrospective study of patients who underwent bur hole craniotomy for CSDH between December 2014 and December 2019 was performed. Demographic and clinical data of age, gender, medication (antithrombotic therapy), smoking, daily alcohol consumption, history of head trauma, presenting symptoms and neurological examination were collected from medical records. Patients were divided into 3 groups according to the time of surgery from referral; 1st group: within 24 hours; 2nd group: between 24 to 72 hours; 3rd group: after 72 hours. Results:In the 5-year period, 117 patients underwent CSDH surgery. 72 of 117 patients were male (61.5%) and 45 of 117 patients were female (38.5%). The mean age was 70.5 ± 7.2 years. Postoperative ASDH was observed in 2 of 32 patients (6.3%) without any antithrombotic medication history and 6 of 85 patients (7.1%) with previous antithrombotic medication history. Preoperative antithrombotic drug usage was not statistically significant in terms of acute complication development (p = 0.797). Conclusion:In this study, we found that the risk of acute hemorrhage due to antithrombotic medication did not differ from those who were not under the medication. Although it is reported in the literature that antiaggregant and anticoagulant drugs should be discontinued between 5 and 7 days before the surgical procedure, our results showed that acute hemorrhage was not detected in any of the patients operated 72 hours after referral

Corresponding author : Mehmet Onur Yüksel