Aim:The aim of this report was to compare the results of fluoroscopically guided transforaminal epidural steroid injection (TESI) for pain reduction in ipsilateral early recurrent lumbar disc herniation (RLDH) with ipsilateral late RLDH.Material and Methods:Seven hundred thirty eight patients complaining of radicular pain due to ipsilateral early and late RLDH were included. Three hundred ninety two subjects were given TESI for ipsilateral early RLDH, and 346 patients were treated for ipsilateral late RLDH. TESIs were carried out based on radicular leg pain, all subjects were followed up and examined again after 12 weeks of therapy. Pre- and post-procedural visual analogue scale (VAS) scores and all complications were recorded for the study.Results:For radicular pain, the mean pre- and post-procedural VAS scores for ipsilateral early RLDH were 85.44 ± 6.85 and 20.16 ± 3.77 respectively. For late RLDH, the mean pre- and post-procedural VAS scores were 72.82 ± 5.12 and 30.87 ± 4.17, respectively. A significant statistical difference for pre- and post-procedural VAS scores were observed between ipsilateral early and late recurrent disc herniation TESI groups (p<0.05) Conclusion:This study demonstrated that TESI was more effective for early RLDH than late RLDH in a 12-week follow-up period.