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¹Fattouma Bourguiba University Hospital, Department of Neurosurgery, Monastir, Tunisia
²Fattouma Bourguiba University Hospital, Department of Pathology, Monastir, Tunisia DOI : 10.5137/1019-5149.JTN.13047-14.3 Congenital glioblastomas are uncommon tumors of infancy with unique molecular features and usually better prognosis compared to their pediatric and adult counterparts. A 15-day old newborn harboring a congenital glioblastoma undiagnosed at pregnancy presented to our emergencies with rapid neurological deterioration. Radiological investigations revealed an 8 by 9 cm space occupying and enhancing lesion in the left temporoparietooccipital region with intratumoral hemorrhage. The patient was immediately transferred to the operative theater and was operated in a poor condition. Unfortunately he showed no improvement post-operatively and died within two days in the intensive care unit. As such presentation is unique; we present the case and review the relevant literature concerning the potential pitfalls in diagnosis, management strategies and improvements in outcome. Keywords : Congenital glioblastoma, Magnetic resonance imaging, Surgery, Chemotherapy, Prognosis