Issue release date: 18.03.2025
Turkish Neurosurgery
2021 , Vol 31 , Num 1
1Istanbul Medipol University, School of Medicine, Department of Medical Pharmacology, Istanbul, Turkey
2Namik Kemal University, School of Medicine, Department of Neurosurgery, Tekirdag, Turkey DOI : 10.5137/1019-5149.JTN.31730-20.1 AIM: To explain how to resect hippocampal tissue in rats used as live mammalian subjects for the resection of fresh cerebral tissue in laboratories.
Corresponding author : Ibrahim YILMAZ, ibrahimyilmaz77@yahoo.com
2Namik Kemal University, School of Medicine, Department of Neurosurgery, Tekirdag, Turkey DOI : 10.5137/1019-5149.JTN.31730-20.1 AIM: To explain how to resect hippocampal tissue in rats used as live mammalian subjects for the resection of fresh cerebral tissue in laboratories.
MATERIAL and METHODS: Adult male Wistar-Albino rats (n=50) were used for this purpose.
RESULTS: The average bodyweight of the rats was 316.4 ± 11.71 g, and the average weight of the resected hippocampal tissues was 1.01 ± 0.03 g; however, there were no statistically significant differences between the body weights and the hippocampal tissue weights (p>0.05). The hippocampal tissues to be used in the study were excised practically by preserving the original anatomical configuration without injury to the tissue.
CONCLUSION: This paper elucidates a simple, step-by-step methodology for performance in the laboratory in order to improve the standardization of hippocampal tissue dissection.
Keywords : Dissection, Brain, Cerebellum, Cortex, Hippocampus, Wistar-Albino, Rat