Issue release date: 23.01.2024
Turkish Neurosurgery
1992 , Vol 2 , Num 4
1Marmara University School of Medicine Department of Neurosurgery, İstanbul- TÜRKİYE
2Marmara University School of Medicine Department of Histology, İstanbul- TÜRKİYE
3Hacettepe University School of Medicine Department of Neurosurgery, Ankara – TÜRKİYE
4Hacettepe University School of Medicine Department of Pathology, Ankara - TÜRKİYE In this study. we evaluated whether Lidocain would reduce ischaemic brain damage and restore bioelectric activity in cats subjected to permanent unilateral occlusion of the middle cerebral artery.
Corresponding author : M. Memet Özek
2Marmara University School of Medicine Department of Histology, İstanbul- TÜRKİYE
3Hacettepe University School of Medicine Department of Neurosurgery, Ankara – TÜRKİYE
4Hacettepe University School of Medicine Department of Pathology, Ankara - TÜRKİYE In this study. we evaluated whether Lidocain would reduce ischaemic brain damage and restore bioelectric activity in cats subjected to permanent unilateral occlusion of the middle cerebral artery.
In the Lidocain treated group there was a statistically significant improvement in the latendes and amplitudes of somatosensory evoked potentials. The treated group showed also a more limited infarct area on the coronal brain sections. Light and electrone microscope examination revealed that the histopathological infarct process was delayed in the treated group.
Keywords : Focal brain ischaemia. Cerebral infarction. Lidocain. Somatosensory evoked potentials