Turkish Neurosurgery 2015 , Vol 25 , Num 6
Metastatic Adenocarcinoma of Unknown Primary in the Bilateral Cerebellopontine Angles: Case Report and Review of the Literature
Dao-Bao ZHANG, Nian-Dong ZHENG
AIm: Previous studies have shown that carvedilol has a neuroprotective effect in animal models of brain ischemia and brain oxidative damage DOI : 10.5137/1019-5149.JTN.7737-12.2 Metastatic adenocarcinoma in bilateral cerebellopontine angles (CPA) is rare. We report a case and review the current literature in order to enhance recognition of metastatic adenocarcinoma in the cerebellopontine angle. A 44-year-old man was referred to the hospital with rightsided diminished hearing for 7 weeks, left-sided facial palsy for 2 weeks, and left-sided sensorineural hearing loss for 1 week. On Magnetic Resonance Imaging (MRI) two tumors in bilateral CPAs were detected. The left-sided tumor was resected and histopathological examination revealed an adenocarcinoma. Many investigations could not find the primary tumor. One should be careful with middle-aged or elderly patients with sudden progressive deficits in the VIIIth or VIIth cranial nerves, particularly in bilateral CPA. Keywords : Adenocarcinoma, Cerebellopontine angle, Metastasis
Corresponding author : Nian-dong Zheng, 453299057@qq.com