Turkish Neurosurgery 2020 , Vol 30 , Num 6
Systematic Evaluation of Desmopressin Administered to Patients with Aneurysmal Subarachnoid Hemorrhage in the Light of the Literature
Numan KARAARSLAN1,Ibrahim YILMAZ2,Feride Sinem AKGUN3,Tezcan CALISKAN1,Hanefi OZBEK2,Ozkan ATES4
1Namık Kemal University, Scholl of Medicine, Department of Neurosurgery, Tekirdağ, Turkey
2Istanbul Medipol University, School of Medicine, Department of Medical Pharmacology, Istanbul, Turkey
3Istanbul Maltepe University, School of Medicine, Department of Emergency Medicine, Istanbul, Turkey
4Istanbul Esenyurt University, Esencan Hospital, Neurosurgery Clinic , Istanbul, Turkey
DOI : 10.5137/1019-5149.JTN.23064-18.1 AIM: To discuss the management of patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) developing after subarachnoid hemorrhage, in a comparative manner in the light of the literature.

MATERIAL and METHODS: Without country or language restrictions, articles with high evidential value found in electronic databases were compared to our patients? data.

RESULTS: After the literature review, three articles were included for systematic evaluation. Desmopressin was administered to the patients for the treatment of hyponatremia, volume contraction, and negative sodium balance caused by SIADH. However, it was not used for preventing re-bleeding.

CONCLUSION: To prevent the development of this complication (SIADH), the use of desmopressin, an analogue of vasopressin, is important in routine clinical practice. Keywords : Desmopressin, Sodium, Subarachnoid hemorrhage, Syndrome of inappropriate antidiuretic hormone secretion, Urine osmolality

Corresponding author : Numan KARAARSLAN, numikara@yahoo.com