Turkish Neurosurgery 2009 , Vol 19 , Num 2
Supratentorial High Grade Astroblastoma: Report of two Cases and Review of the Literature
Rahşan KEMERDERE1, Reza DASHTI2, Mustafa Onur ULU3, Hüseyin BİÇEROĞLU4, Ahu Senem DEMİRÖZ5, Sait ALBAYRAM6, Pamir ERDİNÇLER7
1,2,3,4,7Istanbul University Cerrahpasa Medical Faculty, Department of Neurosurgery, Istanbul, Turkey
5Istanbul University Cerrahpasa Medical Faculty, Department of Pathology, Istanbul, Turkey
6Istanbul University Cerrahpasa Medical Faculty, Department of Radiology, Istanbul, Turkey
Astroblastoma is a rare glial tumor with uncertain histopathological origin and unpredictable clinical behavior. In this report, the authors present two cases of high grade intracerebral astroblastomas. Both tumors occurred in children as supratentorial, well-circumscribed, peripheral masses. The lesions differed radigraphically; one contained a huge cystic component and heterogeneously enhancing mural nodule while the other appeared as a prominently contrastenhancing solid mass lesion. Both patients were treated with surgery and postoperative radiotherapy. They were followed-up long-term and no recurrence of the tumor was detected in either case. We also discussed the radiological and histological characteristics with prognostic features. Keywords : Astroblastoma, Glial tumor, High grade, Pathology, Radiology
Corresponding author : Pamir Erdinçler, pam@istanbul.edu.tr