A 13 month old girl with bilateral subdural empyema that was shown to be caused by Salmonella paratyphi A is presented. Twenty-four cases of subdural empyema caused by Salmonella species/strains are reported in literature. Subdural empyema that is caused by Salmonella paratyphi A has not been described previously. Treatment consists of surgical decompression by craniotomy and systemic antibiotics in this case.