Current Issue

AIM: To evaluate the potential neuroprotective effect of felbamate in a rat model of spinal cord ischemia-reperfusion injury. MATERIAL and METHODS: Twenty-one male Wistar albino rats were randomly assigned to three groups (n=7 each): control, ischemia, and felbamate-treated. Transient spinal cord is...

AIM: To report our experience with the outcomes of open microsurgical management of third ventricular colloid cysts. MATERIAL and METHODS: This retrospective study presents the surgical outcomes of 33 patients who underwent open microsurgical resection—either through the interhemispheric transcallos...

AIM: To evaluate the satisfaction and experiences of patients who underwent awake craniotomy, a relatively uncommon procedure. MATERIAL and METHODS: Following institutional ethics committee approval, data from 60 patients who underwent awake craniotomy between January 2019 and September 2023 were re...

AIM: To present cases of spontaneous cerebrospinal fluid (CSF) rhinorrhea and otorrhea, and to conduct a systematic literature review examining the relationship between benign tumor location and the leak side. MATERIAL and METHODS: A PRISMA-based systematic review was conducted to evaluate studies o...

AIM: To investigate the effects of lacosamide (LCM), an antiepileptic agent, on group 1 metabotropic glutamate receptors (mGluR1 and mGluR5) expression in a temporal lobe epilepsy (TLE) model. MATERIAL and METHODS: Thirty-two rats were divided into 4 groups: (1) only burr hole without intrahippocamp...

AIM: To demonstrate the anatomical framework of the endoscopic sublabial transmaxillary approach (ESTA) to the middle cranial fossa (MCF). MATERIAL and METHODS: Six formalin-fixed human cadaveric heads injected with red and blue silicone were used for endoscopic dissections to define the surgical la...

AIM: To evaluate clinical outcomes, complications, and pathological distribution in patients with lumbar disc herniation (LDH) and/or lumbar spinal stenosis (LSS) undergoing unilateral biportal endoscopic (UBE) surgery. MATERIAL and METHODS: This retrospective study included 127 patients with LDH an...

AIM: To characterize current vertebral augmentation practices among neurosurgeons in Türkiye, with particular emphasis on patient selection, procedural approaches, complication experience, and postprocedure osteoporosis management. MATERIAL and METHODS: A national, cross-sectional, anonymous, web-ba...

AIM: To assess the association between Modic changes (MCs) and clinical outcomes in patients undergoing one-level lumbar fusion surgery. MATERIAL and METHODS: A retrospective cohort study included patients (>18 years) with single-level DDD treated with one-level lumbar fusion from 2016 to 2020 at a ...

AIM: To investigate the effects of short- and long-term intraperitoneal thymoquinone administration on basilar artery morphometry and cerebral perfusion in a subarachnoid haemorrhage (SAH) model. MATERIAL and METHODS: Forty-two adult male Wistar rats were randomly allocated to seven experimental gro...

AIM: To explore presenting status and pre-existing comorbidities in very elderly patients and compare the inpatient management outcomes with younger counterparts in intracerebral hemorrhage (ICH). MATERIAL and METHODS: This ICH database is a retrospective cohort of 814 patients who presented with pr...

AIM: To examine the selective cytotoxic effects of Electro-Capacitive Cancer Therapy (ECCT) on human glioblastoma (GBM) cell lines (U87-MG and T98-G) and to evaluate its impact on normal epithelial cells. MATERIAL and METHODS: U87-MG and T98-G glioblastoma cells, along with Beas-2B normal epithelial...

AIM: To report our experience in implementing functional mapping-guided resection for eloquent diffuse low-grade gliomas (DLGGs) in a low- and middle-income country (LMIC) setting. There are logistical barriers to achieving onco-functional balance through glioma surgery in LMICs. MATERIAL and METHOD...

AIM: To establish an effective predictive model to inform clinical practice for brainstem glioma, a rare and highly aggressive tumor of the central nervous system, given the lack of prior retrospective studies using the SEER database that have included both pediatric and adult patients. MATERIAL and...

Intracranial solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms, and cases of tumor bleeding are rarely seen. While radiographically similar to meningioma, SFTs exhibit a more aggressive clinical course. The mainstay of treatment is surgical resection followed by adjuvant radiotherapy. We...

This case report presents the first simultaneous occurrence of Chiari malformation type 1 and celiac disease in a 27-year-old male patient. To the best of our knowledge, there are no previously published cases in the literature. This rare association suggests that nutrient malabsorption caused by ce...

Neuroenteric cysts (NCs) are rare benign lesions believed to originate from ectopic endodermal tissue. They are lined by gastrointestinal or respiratory epithelium capable of secreting mucin. Although most frequently located within the spinal canal, intracranial NCs are exceedingly rare and typicall...

Localising the lower cervical spine intraoperatively using conventional fluoroscopy with lateral projections has limitations. The main factor limiting the adequate visualisation of the cervicothoracic spaces is the superposition of the shoulder’s structures (soft tissue, muscle, and bone), which cre...