E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 28, Issue 1 (2018)
Full Metin PDF
Original Investigation
Pages: 001-006
DOI: 10.5137/1019-5149.JTN.17866-16.1
AIM: Meningioma literature has many large surgical case series, which have been references of text books and neurosurgical
practice. Many of those series were published when stereotactic radiosurgery (SRS) was not so common or these series were in
terms of World Health Organization (WHO) 2000 clas...
Pages: 007-012
DOI: 10.5137/1019-5149.JTN.18991-16.2
AIM: To evaluate and compare the expression of thioredoxin reductase 1 (TrxR1) in primary and secondary glioblastoma samples.
MATERIAL and METHODS: Surgically resected human glioblastoma samples from 40 patients who underwent surgery at our
institution were extracted from their histopathological s...
Pages: 013-018
DOI: 10.5137/1019-5149.JTN.19111-16.1
AIM: Glioblastoma (GBM) is one of the lethal central nervous system tumors. One of the widely used chemical agents for the
treatment of glioblastoma is temozolomide. It is an orally administered, deoxyribonucleic acid (DNA) alkylating agent. DNA alkylation
triggers the death of tumor cells. Howeve...
Pages: 019-028
DOI: 10.5137/1019-5149.JTN.18697-16.1
AIM: Glioblastoma multiforme (GBM) is one of the malignant brain tumors that occur most frequently. Despite advances in therapy
techniques, the cure of GBM is a major concern. Accordingly, there is a lot of interest in devising novel approaches, such as stem
cell therapy, to treat patients with GB...
Pages: 029-035
DOI: 10.5137/1019-5149.JTN.17474-16.3
AIM: Primary intracranial germinomas (PIGs) are rare malignant brain tumors that represent approximately 0.2% to 1.7% of all
primary intracranial tumors. PIGs have infrequent, but there is a possibility of spinal cord metastases. In this study, clinical outcomes
of five consecutive PIGs have been ...
Pages: 036-042
DOI: 10.5137/1019-5149.JTN.18752-16.1
AIM: Shunt-dependent hydrocephalus (SDH) is a relatively common complication following aneurysmal subarachnoid hemorrhage
(aSAH). Delay in diagnosis and treatment may worsen neurological outcome. This study was conducted to identify early clinical
factors associated with SDH following aSAH.
MATER...
Pages: 043-047
DOI: 10.5137/1019-5149.JTN.18186-16.1
AIM: Clinical treatment of multiple intracranial aneurysms remains challenging due its higher rate of rupture compared to a single
aneurysm. We aimed to assess the efficacy of one-stage endovascular embolization for treatment of multiple intracranial aneurysms.
MATERIAL and METHODS: We treated 72 ...
Pages: 048-055
DOI: 10.5137/1019-5149.JTN.16867-16.3
AIM: To investigate the relationship between neuron density of the superior cervical sympathetic ganglia and pupil diameter in
subarachnoid hemorrhage.
MATERIAL and METHODS: This study was conducted on 22 rabbits; 5 for the baseline control group, 5 for the SHAM group and
12 for the study group. ...
Pages: 056-061
DOI: 10.5137/1019-5149.JTN.18423-16.1
AIM: Micro-vascular anastomosis is a difficult art. It can be learnt and perfected only by practice using vessels of small animals in
the laboratory. The purpose of the study was to practice various anastomotic techniques using rat femoral vessels and study the
patency rates.
MATERIAL and METHODS...
Pages: 062-066
DOI: 10.5137/1019-5149.JTN.18702-16.1
AIM: To evaluate the effectiveness of lumboperitoneal (LP) shunt procedures in the treatment of normal pressure hydrocephalus
(NPH).
MATERIAL and METHODS: A medical record review was conducted to obtain demographic, clinical, laboratory data, as well as
pre-, intra, -postoperative details of 65 p...
Pages: 067-071
DOI: 10.5137/1019-5149.JTN.18349-16.1
AIM: The Chiari Malformation I (CM I) and the tethered cord syndrome (TCS) are both congenital abnormalities whose mechanisms
are still not fully understood. The association of CM I and TCS has been reported only a few times previously.
MATERIAL and METHODS: This retrospective study included 7 pat...
Pages: 072-078
DOI: 10.5137/1019-5149.JTN.18189-16.1
AIM: To evaluate iatrogenic vascular injuries in the craniocervical region and their endovascular management.
MATERIAL and METHODS: Twenty-one patients (9 women, 12 men) with a mean age of 53.6 years (range 16-87 years), who
underwent endovascular embolization for iatrogenic vascular injury in the...
Pages: 079-087
DOI: 10.5137/1019-5149.JTN.18672-16.1
AIM: To evaluate the neurological outcomes of children diagnosed with brain abscesses in the early post-treatment period.<
b>MATERIAL and METHODS: This study was a retrospective analysis of pediatric brain abscess patients between January 2000
and December 2015, during a 16-years period. Patients ...
Pages: 088-093
DOI: 10.5137/1019-5149.JTN.18322-16.1
AIM: To evaluate the long-term efficacy and safety of microvascular decompression (MVD) for treating trigeminal neuralgia (TN),
and identify the predictors of pain relief.
MATERIAL and METHODS: A total of 425 patients who underwent surgery between 1991 and 2011 for idiopathic TN were included
in ...
Pages: 094-098
DOI: 10.5137/1019-5149.JTN.19094-16.2
AIM: To determine whether the Thoracolumbar Injury Classification and Severity Score (TLICS) and the Arbeitsgemeinschaft für
Osteosynthesefragen (AO) Spine Thoracolumbar Injury Classification System have any superiority to each other regarding the
reliability of their recommendations in the surgic...
Pages: 099-104
DOI: 10.5137/1019-5149.JTN.18306-16.1
AIM: To evaluate the perioperative morbidities of patients taking anti-platelet medication prior to multi-level thoracolumbar spine
surgery.
Pages: 105-110
DOI: 10.5137/1019-5149.JTN.17476-16.1
AIM: It is well known that treatment modalities against secondary damage due to spinal cord injury (SCI) are very important. This
phase has been researched in many experimental studies. Apoptosis is one of the major mechanisms of secondary damage on
spinal cord. The present study was undertaken to...
Pages: 111-117
DOI: 10.5137/1019-5149.JTN.18460-16.1
AIM: To investigate the effects of local and systemic administration of etanercept on the formation of epidural fibrosis.
MATERIAL and METHODS: Twenty-eight rats were randomly divided into four equal groups (Control, SpongostanTM, Local
etanercept and Systemic etanercept) and laminectomy was perfo...
Pages: 118-127
DOI: 10.5137/1019-5149.JTN.18009-16.2
AIM: Spinal cord arteriovenous fistulas are rare cause of progressive myelopathy. The predictive factors of their outcome after
endovascular or surgical treatment are still controversial.
MATERIAL and METHODS: Twenty patients were diagnosed with spinal arteriovenous fistulas; 13 of them had dural ...
Pages: 128-136
DOI: 10.5137/1019-5149.JTN.18806-16.0
AIM: Creatine is an endogenous molecule synthesized in the liver, kidney and pancreas from glycine and arginine and is important
for mitochondrial metabolism. It is widely used as a supplement for improving muscle mass and function for many years. As it is
expected to prevent apoptosis and diminis...
Pages: 137-141
DOI: 10.5137/1019-5149.JTN.18677-16.0
AIM: Neonatal intraventricular hemorrhage (IVH) usually results in posthemorrhagic hydrocephalus (PHH). This multicenter study
describes the approach of early neuroendoscopic ventricular irrigation for the treatment of IVH/PHH and compares the results with
the cases that have been initially treate...
Pages: 142-148
DOI: 10.5137/1019-5149.JTN.18072-16.1
AIM: To describe the relationship between the parenchymal pressure changes and the development of hydrocephalus in kaolininjected
neonatal rats according to cerebral regions and time intervals of developing hydrocephalus.
MATERIAL and METHODS: Neonatal rats aged 2 to 3 days were examined in 5 grou...
Case Report
Pages: 149-151
DOI: 10.5137/1019-5149.JTN.14570-15.1
We describe herein intraoperative effectiveness of indocyanine green (ICG) video angiography to confirm dural arteriovenous
fistulae. A 62-year-old man with a residual symptomatic dural arteriovenous fistula that was previously embolized at another
institution is presented. On neurological examina...
Pages: 152-157
DOI: 10.5137/1019-5149.JTN.15052-15.1
All patients were acute, multi-segment cervical spinal cord compression injury secondary to subaxial cervical spine fracture. These
patients underwent emergency posterior cervical pedicle screw-rod/plate instrumentation combined with unilateral open-door
laminoplasty. Well-placed pedicle screws an...
Pages: 158-163
DOI: 10.5137/1019-5149.JTN.14780-15.2
The surgical approaches for spinal tumors, to a great extent, have been developed in accordance with the developments in medical
technology. Today, many surgical techniques are implemented as anterior, anterolateral, posterior, posterolateral and combined
approaches. Due to its low morbidity, the ...
Letter to Editor
Pages: 164-165
DOI: 10.5137/1019-5149.JTN.18997-16.0
Pages: 166
DOI: 10.5137/1019-5149.JTN.19032-16.0