E-ISSN: 1019-5157 ISSN: 2651-5024
Original Investigation
AIM: To investigate whether high dose toxicities of etoposide can be overcome when used in combination with a natural compound named Rosmarinus Officinalis for glioblastoma (GBM). MATERIAL and METHODS: The impact of Rosmarinus Officinalis in combination with etoposide on GBM U87 MG cells and Mouse...
AIM: To evaluate the neuroprotective effects of deocanthal OC in a rat model of traumatic brain injury (TBI). MATERIAL and METHODS: Twenty-six adult male, Wistar albino rats were used. The rats were divided into 4 groups. Group 1 was the sham group (n=5). Group 2 was the trauma group (n=5) where r...
AIM: To use a smartphone application (app) during pedicle screw placement navigation and examine the accuracy of this application on an anatomical dry vertebrae model. MATERIAL and METHODS: Seventy-six dry vertebrae were used for this study, and pedicle entry points and projections of pedicle scr...
AIM: To accurately describe the relations between the anatomical landmarks of the cranial convexity and the main cortical structures. MATERIAL and METHODS: A retrospective cross-sectional, observational study was performed. Computed tomography scans of 71 adult patients with no pathological imagin...
AIM: To investigate the outcomes and associated complications after delayed cranioplasty using autologous, cryopreserved bone. MATERIAL and METHODS: This retrospective study included 57 consecutive patients treated with cranioplasty with autologous cryopreserved bone for various conditions causing...
AIM: To determine the effects of resveratrol on inflammation and apoptosis after experimental spinal cord injury (SCI). MATERIAL and METHODS: Eighteen Sprague-Dawley rats were randomly divided into three groups. All groups underwent thoracic laminectomy. The first group received no other intervent...
AIM: To reveal the potential relationships and interactive effects between frailty and body weight and adverse surgical outcomes for degenerative spinal disease. MATERIAL and METHODS: Patients who underwent open surgery for degenerative spinal disease in our hospital were included. Data on the pa...
AIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant infections. MATERIAL and METHODS: A total of 166 consecutive lumbar steno...
AIM: To investigate the expression of cancer stem cell markers in meningiomas. MATERIAL and METHODS: CD133, Nestin and Sox2 expression levels in 35 paraffin-embedded meningioma tissue samples were assessed using immunohistochemistry. RESULTS: In this study, five cases were atypical (WHO Grade II)...
AIM: To compare sinonasal complications after microscopic and endoscopic approaches for pituitary adenomas. MATERIAL and METHODS: At our clinic, sinonasal complications occurred in 31 patients who underwent microscopic transsphenoidal surgery between 2007 and 2014 and in 32 patients who underwent ...
AIM: L5/S1 Adolescent lumbar disc herniation (ALDH) is usually ignored for its low incidence. Recently, percutaneous endoscopic procedures have been widely used. To investigate the surgical techniques and clinical outcomes of percutaneous endoscopic interlaminar discectomy (PEID) in the treatment ...
AIM: To investigate the costs of treating the infection with antibiotics only with the risk of surgery when unsuccessful versus immediate removal followed by re-implantation in patients with deep brain stimulation (DBS) hardware infection. MATERIAL and METHODS: We calculated the costs of the diffe...
AIM: Dissection of white fibers is important in identifying detailed neuroanatomical relationships. With tractrography it is possible to transport and apply this knowledge in a practical way to treat many diseases involving the white matter. MATERIAL and METHODS: The Klingler method, subsequently d...
AIM: To discuss a special type of skull lesion detected after delivery. We reviewed our experience on scalp swelling in term neonates to further investigate the relationship between cranial injuries and labor process. MATERIAL and METHODS: A total of 55 newborns with scalp swellings were assessed ...
AIM: To evaluate the existence of nerve innervation of the triceps brachii muscle via the ulnar nerve and its clinical importance in terms of nerve transfer or susceptibility to iatrogenic injuries during surgical procedures. MATERIAL and METHODS: Thirty-five skeletally mature upper extremities of...
AIM: To evaluate bevacizumab for epidural fibrosis (EF) treatment in an experimental rat model using histopathology as well as immunohistochemical staining for CD105 and osteopontin (OPN). MATERIAL and METHODS: Sixteen Wistar Albino rats underwent either laminectomy alone to induce EF (group I, co...
AIM: To evaluate the cerebrospinal fluid (CSF) flow dynamics in the aqueductus sylvii of patients with obstructive hydrocephalus who underwent endoscopic third ventriculostomy (ETV) and to predict ventriculostomy patency via aqueduct flow measurements. MATERIAL and METHODS:Twenty-four patients wit...
AIM: To present our experience of 225 clipped aneurysms in 196 patients to compare indocyanine green video angiography (ICGVA), micro-Doppler ultrasonography (MDUSG), and postoperative digital subtraction angiography (DSA) in terms of determining aneurysm obliteration, neck remnants, and parent ar...
AIM: To evaluate postoperative clinical outcome and recurrence rates in cases with ventrally located spinal meningiomas who underwent Simpson grade 2 resection. MATERIAL and METHODS: We evaluated eight cases (six females and two males; age, 28?86 years; mean age, 60 years) with ventrally located ...
AIM: To investigate the clinical characteristics and prognostic factors that may influence outcomes of patients undergoing benignappearing intraspinal malignant peripheral nerve sheath tumors (MPNSTs). MATERIAL and METHODS: This study included a total of 14 consecutive patients who were diagnosed ...
AIM: To investigate the possible role of ELABELA (ELA) in the histopathological grading of gliomas. MATERIAL and METHODS: We retrospectively assessed pathological specimens of patients who underwent surgery for intracranial space-occupying lesions. Only primary glioma specimens were included in th...
AIM: To compare four different atlantoaxial stabilization techniques. MATERIAL and METHODS: Eight human cervical spines (segments C0-C3) were tested in flexion/extension, lateral bending and axial rotation. Range of Motion (ROM) at a 1.5 Nm load was recorded. After native testing, the Harms (HARMS...
Case Report
The primitive neuroectodermal tumors (PNETs) of the spine are rare. They are usually intramedullary and reported in children. We herein report an epidural PNET of lumbosacral area presenting with the cauda equina syndrome in an adult. A 38-year-old woman presented to our emergency room with acute ...
Rebleeding of cerebral aneurysms has been previously reported during diagnostic angiography. However, capturing the exact moment of active rebleeding of a cerebral aneurysm during angiography is extremely rare. Here, a case of a rebleeding middle cerebral artery aneurysm during diagnostic digital ...
Letter to Editor
Thanks to Reviewers