E-ISSN: 1019-5157 ISSN: 2651-5024
Turkish Neuro -Excursion
Since the inception of the International Fellowship (IF) Program in the Department of Neurological Surgery at the University of Wisconsin-Madison in 2006, training has been provided to 219 residents, neurosurgeons, and medical students from 18 countries and five continents. These IFs took a long a...
Original Investigation
AIM: To investigate the effects of an anti-ischemic agent, mildronate, on subarachnoid hemorrhage-induced vasospasm. MATERIAL and METHODS: Rabbits were randomly divided into four groups: control, subarachnoid hemorrhage (SAH), vehicle, and mildronate (n=8 animals per group). In the treatment group...
AIM: To investigate the clinicopathological features and related factors affecting microsurgical resection of lesions in the cavernous sinus. MATERIAL and METHODS: Clinical data of 66 patients undergoing microsurgery for lesions located in the cavernous sinus from January 2011 to December 2017 we...
AIM: To investigate the magnetic resonance imaging (MRI) results of patients complaining from diplopia with ocular nerve palsy. MATERIAL and METHODS: A routine ophthalmic examination was performed, a neurological consultation was requested, and cranial MRI was performed for all patients. The image...
AIM: To determine the interaction between ruxolitinib, JAK/STAT signalling, and two angio-microRNAs (miRs) to expose potential target molecules in the inhibition of glioblastoma invasion. MATERIAL and METHODS: The invasion properties of glioblastoma were analyzed using a cancer cell spheroid invas...
AIM: To present the clinical results in patients with minor instability with “Dynesys®” a soft spinal stabilization system. MATERIAL and METHODS: A total of 83 patients were operated upon and the Dynesys® system was applied. Indications for surgery included painful degenerative disc disease,...
AIM: To define the optimal time of shunt insertion in patients with neural tube defects and hydrocephalus. MATERIAL and METHODS: In total, 71 patients who underwent operation for neural tube defects and hydrocephalus were retrospectively evaluated between 2012 and 2018. The first group comprised 4...
AIM: To propose a convolutional neural network (CNN) for the automatic detection of high-grade gliomas (HGGs) on T2-weighted magnetic resonance imaging (MRI) scans. MATERIAL and METHODS: A total of 3580 images obtained from 179 individuals were used for training and validation. After random rotat...
AIM: To examine the morphological features of thoracic pedicles in a Turkish population. MATERIAL and METHODS: This retrospective study was performed with the patients who were underwent thoracic CT for any reason such as trauma or pulmonary disorder. Patient’s age, height, weight, and sex were ...
AIM: To investigate the role of bipolar electrocautery in the occurrence of epidural fibrosis following lumbar spine laminectomy in a rat model. MATERIAL and METHODS: Fourteen male Sprague–Dawley rats (age: 4–6 months, weight: 250–300 g) were randomly divided into two groups, a bipolar grou...
AIM: To evaluate the clinical characteristics of children who recently underwent decompressive craniectomy (DC) due to elevated intracranial pressure (ICP) correlated to head trauma or other causes, such as ischemic insult. MATERIAL and METHODS: Twelve patients aged ≤17 years who underwent DC du...
AIM: To determine the efficacy and safety of microvascular decompression (MVD) for hemifacial spasm (HFS) by retrospectively reviewing our results. MATERIAL and METHODS: A total of 55 patients who underwent MVD in our clinic between 2003 and 2017 were retrospectively analyzed. Clinical outcome re...
AIM: To examine the effect of sevoflurane, a halogenated anesthetic used in clinical applications, on oxidative stress and inflammation after an acute traumatic brain injury (TBI) in rats. MATERIAL and METHODS: Thirty male Sprague–Dawley rats were divided into three groups: control (Group 1), tr...
AIM: To evaluate the effect of FSLLRY-NH2, a protease-activated receptor 2 (PAR2) inhibitor, on neurocognitive impairment and hippocampal neuronal degeneration in the setting of asphyxial cardiac arrest (ACA)-induced global cerebral ischemia (GCI) in rats. MATERIAL and METHODS: A total of 43 Sprag...
AIM: To analyze the impact of intraoperative neurophysiological monitoring (IONM) on the extent of removal and long-term neurological outcomes in a series of grade II ependymomas. MATERIAL and METHODS: We retrospectively reviewed 88 consecutive patients who underwent surgical resection of an intr...
AIM: To compare the efficacy of bone graft, hydroxyapatite coralline (Biocoral®), and porous polyethylene (Medpor®) implants for cranioplasty in a rat model of cranial bone defects. MATERIAL and METHODS: Two parietal bone defects were created in each of 16 male Sprague–Dawley rats. One was rep...
AIM: To evaluate the relationship between trigeminal neuralgia (TN) and potential magnetic resonance imaging (MRI)-related measurements in patients with TN. MATERIAL and METHODS: Retrospective analysis of 104 patients with TN was performed. MRI studies of 98 healthy controls were included in the ...
AIM: To assess spatiotemporal gait parameters in patients with lumbar disc herniation (LDH) and chronic mechanical low back pain (CMLBP), and compare with healthy control group. MATERIAL and METHODS: A total of 70 patients was enrolled in this prospective, controlled cross-sectional study, of whic...
AIM: To summarize the clinical outcomes, follow-up results and to discuss the optimal therapeutic strategy for pericallosal artery aneurysms (PAAs). MATERIAL and METHODS: From January 2013 to May 2017, the charts of 49 patients with PAAs, representing 2.43% of 2,018 consecutive patients with intr...
AIM: To determine whether callosal angle (CA) measurement, a diagnostic and prognostic tool used for normal-pressure hydrocephalus in adults, is a reliable radiological parameter for evaluating endoscopic third ventriculostomy (ETV) outcomes in pediatric patients. MATERIAL and METHODS: Forty-seve...
Case Report
Composite hemangioendothelioma (CHE) is a very rare, low-grade malignant vascular tumor. It is most commonly seen as one or more nodules on both sides of the fingers and toes. This tumor rarely settles in the paraspinal muscles. The age of onset is usually between 21 and 72 years, with an average ...
Intracranial chondromas are unusual benign tumors. They commonly occur at the base of the skull, whereas an intraventricular type is very rare. We present the case of a 19-year-old female patient with a giant intraventricular chondroma detected incidentally by imaging after a car accident. The sp...
Spinal intradural arachnoid cysts (SIACs) are cerebrospinal fluid (CSF) sacs formed by arachnoid membranes. They may be idiopathic or acquired. Treatment is resection, fenestration, or cyst drainage. A 41-year-old female patient presented with myelopathy symptoms and complaints. Magnetic resonance...
Technical Note
Removing a broken pedicle screw is not always easy. Different methods and tools have been developed to remove the broken screw. Preserving the pedicle is an advantage for re-instrumentation. The head of the broken screw can be modified with the aid of a high-speed drill and the screw can be remove...
Letter to Editor