E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 31, Issue 2 (2021)
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Review
Pages: 151-160
DOI: 10.5137/1019-5149.JTN.31405-20.2
AIM: To evaluate the clinical outcomes of incidental meningiomas (IM) treated with stereotactic radiosurgery (SRS) or observation.
MATERIAL and METHODS: The PubMed, Cochrane Library and MEDLINE (Ovid) databases were comprehensively searched for
eligible studies about IM that were managed with seri...
Original Investigation
Pages: 161-166
DOI: 10.5137/1019-5149.JTN.27841-19.2
AIM: To analyze retrospectively our experience of unilateral hemilaminectomy in intradural extramedullary (IDEM) tumors.
MATERIAL and METHODS: This study included 28 patients with IDEM tumors who underwent unilateral hemilaminectomies
during the period 2011?2016. The preoperative clinicoradiologic...
Pages: 167-172
DOI: 10.5137/1019-5149.JTN.29244-20.2
AIM: To clarify the risk factors for adult moyamoya disease (MMD) in patients from South China.
MATERIAL and METHODS: We prospectively studied adult patients who were diagnosed angiographically with MMD. The
demographic profiles, medical history and clinical characteristics were compared between a...
Pages: 173-181
DOI: 10.5137/1019-5149.JTN.29896-20.2
AIM: To perform three-level decompression with a single-level corpectomy by modifying the fusion with anterior cervical corpectomy
(ACC-F) method on a cadaver.
MATERIAL and METHODS: The anterior cervical region of four whole-head cadavers was dissected. The corpectomy was
performed under a surgic...
Pages: 182-188
DOI: 10.5137/1019-5149.JTN.28328-19.1
AIM: To demonstrate a custom spine disease analytical evaluation module that can instantly, accurately, and effectively analyze the
widely accepted outcome measurements.
MATERIAL and METHODS: The data input and analysis processes were evaluated on a timely basis to compare the traditional
paper-b...
Pages: 189-198
DOI: 10.5137/1019-5149.JTN.29489-20.5
AIM: To examine the implantation of chitosan channels stuffed with mesenchyme-originated stem/progenitor cells (MSPCs) derived
from adult rats in a spinal cord transection model. The level of axonal regeneration, the effect of chitosan channels on the survival
of MSPCs, and the functional recovery...
Pages: 199-205
DOI: 10.5137/1019-5149.JTN.29765-20.2
AIM: To compare the clinical and radiological results of using synthetic bone graft versus autograft obtained from the spinous
process in posterior lumbar interbody fusion.
MATERIAL and METHODS: This retrospective study included 102 patients with degenerative lumbar spondylolisthesis who
underwen...
Pages: 206-210
DOI: 10.5137/1019-5149.JTN.30316-20.1
AIM: To investigate the cytotoxic effects of boron application at different doses on U-87 MG glioblastoma cells.
MATERIAL and METHODS: The T98G (ATCC® CRL-1690?) glioblastoma cell strain used in the study was acquired from the
American Type Culture Collection (ATCC) (Manassas, USA). Boric acid sol...
Pages: 211-216
DOI: 10.5137/1019-5149.JTN.30237-20.2
AIM: To evaluate the protective effects of azathioprine, a macrophage-inhibiting agent, on secondary injury in spinal cord trauma.
MATERIAL and METHODS: A total of 40 Wistar rats were randomly divided into 4 groups. All the animals had undergone T8-10
laminectomy. Except in group I (control), all ...
Pages: 217-222
DOI: 10.5137/1019-5149.JTN.30673-20.1
AIM: To demonstrate the microsurgical procedures, and to evaluate the feasibility of living models of experimental neurovascular
training by developing new complex vascular exercises mimicking the most common intracranial aneurysms.
MATERIAL and METHODS: The procedures were performed under a Zeiss...
Pages: 223-227
DOI: 10.5137/1019-5149.JTN.30774-20.4
AIM: To determine the effect of Intravenous Tranexamic Acid (TXA) on traumatic intracerebral hemorrhage.
MATERIAL and METHODS: A total of 94 cases of TBI with intracerebral hemorrhage, admitted to the emergency department who
did not need surgical intervention based on a primary brain spiral compu...
Pages: 228-232
DOI: 10.5137/1019-5149.JTN.29081-20.4
AIM: To measure the serum levels of strong angiostatic and synaptogenetic molecules thrombospondin-1 (TSP-1) and
thrombospondin-2 (TSP-2) in patients with temporal lobe epilepsy (TLE) before and after surgery.
MATERIAL and METHODS: In this prospective study, 20 patients operated for TLE and 20 hea...
Pages: 233-237
DOI: 10.5137/1019-5149.JTN.29176-20.3
AIM: To investigate the effects of metformin, dichloroacetate (DCA), and memantine on T98G and U87-MG human glioblastoma
(GBM) cells to target tumor cell metabolism in a multi-directional manner.
MATERIAL and METHODS: IC50 levels for metformin, DCA, metformin+DCA and memantine were determined by M...
Pages: 238-246
DOI: 10.5137/1019-5149.JTN.29712-20.2
AIM: To analyze the effectiveness of fat and fibrin glue to prevent postoperative cerebrospinal fluid (CSF) leak in pituitary surgery.
MATERIAL and METHODS: Two hundred and eleven patients affected by pituitary adenoma entered this study. Patients that
underwent a microscopic transsphenoidal appro...
Pages: 247-253
DOI: 10.5137/1019-5149.JTN.30784-20.3
AIM: To evaluate the functional and histopathological results of alpha-tocopherol (vitamin E) and vitamin B12 on an experimental rat
model of peripheral nerve injury.
MATERIAL and METHODS: This research included 32 Wistar Hannover rats. The sciatic nerves of the animals were crushed using
an aneu...
Pages: 254-260
DOI: 10.5137/1019-5149.JTN.30786-20.2
AIM: To compare the histological and angiographic measurements of the basilar artery in an experimental rabbit subarachnoid
hemorrhage model.
MATERIAL and METHODS: The basilar artery was measured using both histological and angiographic methods in experimental
subarachnoid hemorrhage (SAH) and va...
Pages: 261-267
DOI: 10.5137/1019-5149.JTN.30527-20.4
AIM: To estimate the rupture risk of anterior communicating artery (AComA) and AComA-related aneurysms according to their
localization, angiographic architecture, and morphological features.
MATERIAL and METHODS: In this study, 124 patients with AComA and AComA-related anterior system aneurysms we...
Pages: 268-273
DOI: 10.5137/1019-5149.JTN.32092-20.1
AIM: To investigate the effects of different radiation doses on the development of the neural tube defect in chick embryos using
computed tomography (CT), and assess its correlation with survivin and Bcl-2 expressions.
MATERIAL and METHODS: A total of 150 chicken eggs were used and grouped into fi...
Pages: 274-281
DOI: 10.5137/1019-5149.JTN.32341-20.2
AIM: To define the natural course of kyphosis, and to evaluate the efficiency of a new technique in surgical correction of kyphosis
seen in myelomeningocele(MM) patients.
MATERIAL and METHODS: We retrospectively reviewed our patients with MM. The rate of kyphosis, mean angle of progression
and me...
Pages: 282-289
DOI: 10.5137/1019-5149.JTN.31866-20.2
AIM: To assess and compare the antioxidant capacities of high-grade gliomas (HGG) according to their grades and the presence of
isocitrate dehydrogenase 1 (IDH1) mutation using tissue thiol level measurement.
MATERIAL and METHODS: Tissue thiol concentrations were measured in 41 HGG samples and 21 ...
Technical Note
Pages: 290-295
DOI: 10.5137/1019-5149.JTN.31433-20.5
The mediobasal temporal region (MTR) is a deep part of the brain covered by eloquent structures. In certain cases, accessing this
region is challenging. According to the literature, the supracerebellar transtentorial (SCTT) approach provides safe access to the
MTR. Since this approach was introduc...
Systematic Review
Pages: 296-297
DOI: 10.5137/1019-5149.JTN.32961-20.0
Letter to Editor
Pages: 298-298
DOI: 10.5137/1019-5149.JTN.31801-20.1
Pages: 299-300
DOI: 10.5137/1019-5149.JTN.31817-20.2