E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 32, Issue 3 (2022)
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Review
Pages: 347-356
DOI: 10.5137/1019-5149.JTN.34816-21.1
AIM: To review the correlation between vitamin D (VD) and several common neurological disorders with the aim of providing
directions and ideas for using VD to treat neurological disorders.
MATERIAL and METHODS: VD, 1,25-dihydroxyvitamin D3, stroke, epilepsy, and cognitive dysfunction were used as ...
Original Investigation
Pages: 357-363
DOI: 10.5137/1019-5149.JTN.26278-19.2
AIM: To study the relationship between temozolomide (TMZ) chemotherapy-resistant cells and stem cells in gliomas.
MATERIAL and METHODS: The U251 glioma cell line was exposed to TMZ to generate TMZ-resistant colonies (U251/TMZ cell
line) using the pulse drug method. The TMZ sensitivity of U251/TMZ ...
Pages: 364-371
DOI: 10.5137/1019-5149.JTN.35036-21.3
AIM: To analyze the clinical characteristics of thoracic ossified ligamentum flavum (OLF) and clarify prognostic factors.
MATERIAL and METHODS: We retrospectively collected clinical data from the medical records of 29 patients who underwent
decompressive surgery for myelopathy caused by thoracic O...
Pages: 372-377
DOI: 10.5137/1019-5149.jtn.32196-20.2
AIM: To evaluate the extrinsic dorsal venous pattern of spinal cord at the thoracolumbar level hypothesizing that any variant of these
intrathecal venous pattern as probable factor for post lumbar pucture hemorrhagic complications.
MATERIAL and METHODS: In a tertiary teaching institution, 25 adult...
Pages: 378-385
DOI: 10.5137/1019-5149.JTN.32324-20.2
AIM: To investigate the effects of midazolam (MDZ) and thiopental on neonatal and adult rat brains.
MATERIAL and METHODS: The study included adult and 7-day-old rats that were administered 9 mg/kg of MDZ, 60 mg/kg of
thiopental, or both. The Bax, procaspase-3, and caspase-3 levels were assessed us...
Pages: 386-391
DOI: 10.5137/1019-5149.JTN.33806-21.2
AIM: To present one of the largest retrospective cavernoma related epilepsy (CRE) studies which include divergent supratentorial
locations operated and followed up at least 2 years. We also investigated the factors affecting the seizure outcome.
MATERIAL and METHODS: This study includes a total of...
Pages: 392-397
DOI: 10.5137/1019-5149.JTN.34519-21.2
AIM: To evaluate the effects of factors, which are associated with carpal tunnel syndrome (CTS) prevalence, on disease severity.
MATERIAL and METHODS: This retrospective study included 206 patients who were treated surgically for either moderate or
severe CTS. Patients were grouped into moderate a...
Pages: 398-405
DOI: 10.5137/1019-5149.JTN.33808-21.2
AIM: To investigate the effects of subthalamic deep brain stimulation (STN DBS) therapy on sleep quality of Parkinson?s Disease
(PD) patients and the relationship between sleep, motor symptoms, depression, and adverse effects of dopamine replacement
therapies.
MATERIAL and METHODS: A total of 26 ...
Pages: 406-411
DOI: 10.5137/1019-5149.JTN.35393-21.2
AIM: To present the quantitative development of the geniculate ganglion (GG) in foetal cadavers.
MATERIAL and METHODS: This study focused on 60 temporal bones of 30 (15 female and 15 male) foetuses aged 18?30 weeks
of gestation (mean age, 22.83 ± 3.49 weeks) to measure the length, width and area o...
Pages: 412-419
DOI: 10.5137/1019-5149.JTN.34904-21.2
AIM: To evaluate the effects of dexamethasone (Dex) treatment on neural crest cells and primary and secondary neurulation in chick
embryos.
MATERIAL and METHODS: Sixty fertilized eggs with an average weight of 65 ± 2 g were incubated in 60%?70% humidity at 37.2°C
± 0.1°C. After 26 hours of incuba...
Pages: 420-429
DOI: 10.5137/1019-5149.JTN.34917-21.3
AIM: To investigate the supplementation of alpha-lipoic acid (ALA) at the molecular level to determine its effect on primary cell
cultures prepared from human intervertebral disc (IVD) tissue in an in vitro environment.
MATERIAL and METHODS: Human primary cell cultures were prepared from IVD tissu...
Pages: 430-441
DOI: 10.5137/1019-5149.JTN.34984-21.2
AIM: To compare gene expression profiles between atypical meningiomas and normal meninges from the National Center of
Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) database to identify key genes and pathways.
MATERIAL and METHODS: The microarray datasets GSE43290 and GSE16581 were...
Pages: 442-448
DOI: 10.5137/1019-5149.JTN.35810-21.2
AIM: To compare preoperative and postoperative sexual dysfunction in male patients diagnosed with lumbar disc herniation (LDH).
MATERIAL and METHODS: This study was conducted in a single group with a pretest?posttest design. The sample included 32
male patients with LDH admitted to the neurosurger...
Pages: 449-458
DOI: 10.5137/1019-5149.JTN.35635-21.2
AIM: To examine the postoperative outcomes of electrode fixation using bone cement and Stimloc® in patients with Parkinson?s
disease (PD) who underwent subthalamic nucleus (STN) deep brain stimulation (DBS).
MATERIAL and METHODS: Between 2016 and 2018, permanent electrode fixation was performed in...
Pages: 459-465
DOI: 10.5137/1019-5149.JTN.35996-21.1
AIM: To present an early warning system (EWS) that employs a supervised machine learning algorithm for the rapid detection of
extra-axial hematomas (EAHs) in an emergency trauma setting.
MATERIAL and METHODS: A total of 150 sets of cranial computed tomography (CT) scans were used in this study wit...
Pages: 466-470
DOI: 10.5137/1019-5149.JTN.35997-21.1
AIM: To reveal the reliability and validity of the Turkish Lumbar Spine Instability Questionnaire for evaluating patients with lumbar
instability and low back pain.
MATERIAL and METHODS: A total of 100 patients with low back pain participated in the study. Test-retest and internal consistency
ana...
Pages: 471-480
DOI: 10.5137/1019-5149.JTN.35974-21.2
AIM: To determine the rate of postoperative complications following surgery for Scheuermann?s kyphosis (SK) and ascertain whether
restoration to an ideal Roussouly spine type reduced the incidence of postoperative proximal junctional kyphosis (PJK).
MATERIAL and METHODS: We retrospectively screene...
Pages: 481-487
DOI: 10.5137/1019-5149.JTN.36470-21.3
AIM: To observe the effects of prone position extubation on respiratory side effects and hemodynamic parameters in patients who
underwent lumbar spinal surgery.
MATERIAL and METHODS: This prospective observational study included 60 patients extubated in either the prone (n=30) or supine
(n=30) po...
Pages: 488-499
DOI: 10.5137/1019-5149.JTN.37742-22.1
AIM: To investigate the spatiotemporal dynamics of early cerebral blood flow (CBF) changes, cerebrovascular reactivity (CVR), and
vascular responses to cortical spreading depolarization (CSD) in an experimental mild traumatic brain injury (mTBI) model with laser
speckle contrast imaging (LSCI) tec...
Pages: 500-507
DOI: 10.5137/1019-5149.JTN.40005-22.2
AIM: To evaluate isocitrate dehydrogenase (IDH) mutation status and Ki67 percentages of tumors that were treated in our institution
to determine whether these markers affected the initial diagnosis and survival rates.
MATERIAL and METHODS: High-grade glioma patients, who were operated in our depar...
Case Report
Pages: 508-512
DOI: 10.5137/1019-5149.JTN.34938-21.1
AIM: To report the first case of an isolated lumbar grade II atypical choroid plexus papilloma (CPP).
CASE REPORT: A 42-year-old man was admitted to the hospital because of back and leg pain. No urinary or rectal dysfunction was
detected. Lumbar magnetic resonance imaging (MRI) showed a well-circu...
Pages: 513-516
DOI: 10.5137/1019-5149.JTN.35424-21.3
AIM: Deep brain stimulation (DBS) is a well-established treatment option for improving function and quality of life (QoL) in carefully
selected patients with Parkinson?s disease (PD). Patient selection is a crucial step that should be performed by an experienced
multidisciplinary team according to...
Technical Note
Pages: 517-520
DOI: 10.5137/1019-5149.JTN.34847-21.3
AIM: To report the retrograde technique of horizontal stenting through the PCoA using a Solitaire AB stent.
MATERIAL and METHODS: A self-expandable stent was deployed from one posterior cerebral artery to the opposite, across the
neck of a ruptured wide-neck basilar apex aneurysm.
RESULTS: The te...
Letter to Editor
Pages: 521
DOI: 10.5137/1019-5149.JTN.36871-21.2
Pages: 522
DOI: 10.5137/1019-5149.JTN.37020-21.1
Pages: 523
DOI: 10.5137/1019-5149.JTN.37470-21.0