E-ISSN: 1019-5157 ISSN: 2651-5024
Original Investigation
AIM: To describe a novel surgical approach to decrease the complication and recurrence rates of medulloblastomas. MATERIAL and METHODS: A retrospective review was performed. The novel technique was performed under similar conditions for all patients. The technique involved early intra-operative id...
AIM: To evaluate the bilateral vertical bipedicled procedure for the closure of large meningomyelocele defects and to emphasise some technical and clinical considerations. MATERIAL and METHODS: This procedure was used to close large meningomyelocele defects in ten patients (six males and four fem...
AIM: To investigate the suppression of aquaporin-4 (AQP4) synthesis through intracerebroventricular (i.c.v.) injection of antisense oligonucleotide after focal cortical contusion injury in mice. MATERIAL and METHODS: This study used 12-week-old female Swiss albino mice (weight, 20-25 g) to create ...
AIM: To investigate the effects of necrostatin-1 (NEC-1) on subarachnoid hemorrhage (SAH)-induced vasospasm in a rat model. MATERIAL and METHODS: A total of 59 male Wistar albino rats were randomly divided into six groups: control (group 1), sham (group 2), decapitation one hour after SAH (group 3...
AIM: To reveal the relation between postdiscectomy syndrome and foraminal stenosis due to height loss of disc level in patients operated for one-sided L5-S1 disc herniation. MATERIAL and METHODS: In this study, 100 operated patients due to L5-S1 one-sided disc herniation were included. Mean age w...
AIM: To investigate the regenerative potential and long-term functional effects of uridine treatment in a rat model of sciatic nerve injury. MATERIAL and METHODS: Male Sprague-Dawley rats were randomized to receive sham surgery plus saline (Sham group), right sciatic nerve transection and primary...
AIM: To examine the relationship between the morphologic features of the internal carotid artery (ICA) and symptoms affecting cerebral blood circulation including type 2 diabetes mellitus (T2DM) and hypertension (HT). MATERIAL and METHODS: In this study, retrospective morphometric analysis of ICA ...
AIM: To evaluate the parameters that affect bone retropulsion and restoration in patients with thoracolumbar junction (TLJ) vertebral compression fractures (VCF) without neurological deficits who underwent balloon kyphoplasty (BKP). MATERIAL and METHODS: Thirty-one of Frankel E and Arbeitsgemeinsc...
AIM: To determine the prevalence, location, and dimensions of interthalamic adhesions (ITAs) in Indian brains. MATERIAL and METHODS: We examined 100 human brains [50 cadaveric and 50 magnetic resonance (MR) images] in the midsagittal plane for the presence or absence of ITAs, their location in the...
AIM: To evaluate the surgical experience of the senior neurosurgeon to define the lesion, radiology, and technique-related factors that affect the diagnostic yield and complications, along with the literature review. MATERIAL and METHODS: Documents were examined for consecutively performed frame-b...
AIM: To reveal the roles of CXCL13 and miR-186-5p in a rat model (adult male Sprague-Dawley rats, 7?8 weeks old, 180?200 g) of trigeminal neuralgia (TN) established via chronic constriction injury of the infraorbital nerve (ION-CCI). MATERIAL and METHODS: The results of behavioural tests and the e...
AIM: To investigate the recurrence rate of atypical meningiomas after surgery (with or without adjuvant radiotherapy), and to determine which factors were related with recurrence. MATERIAL and METHODS: Data obtained from 83 patients who underwent surgery and histopathologically diagnosed with aty...
AIM: To assess the current situation in Greece regarding medical liability in neurosurgery, the involvement of anaesthetists in court decisions, the impact of court cases and decisions, the time taken to reach a final decision, and the relationship between these issues and judicial results. MATER...
AIM: To examine a series of surgically treated spinal arachnoid cysts in light of the literature. MATERIAL and METHODS: This was a retrospective study of patients treated in the Istanbul Umraniye Training and Research Hospital Neurosurgery Clinic. A total of 18 patients with spinal arachnoid cysts...
AIM: To evaluate normal pressure hydrocephalus (NPH) patients who admitted to clinic with a walking disability, depressed mood, cognitive dysfunction, and compromised quality of life in order to create a system for minimizing misdiagnosis, and inaccurate treatment of NPH at the first instance. MA...
AIM: To evaluate the effect of early myelotomy on glutamate concentrations in injured spinal cord tissue with a weight drop spinal cord injury rat model. MATERIAL and METHODS: The rats were assigned randomly to one of four groups, as follows: in group I, rats underwent laminectomy; group II, myel...
AIM: To introduce a new mathematical formula to predict sagittal vertical axis (SVA) changes after lumbar pedicle subtraction osteotomy (PSO). MATERIAL and METHODS: This cross-sectional study included 43 patients. Lateral full spinal radiographs were exported from Picture Archiving and Communicat...
AIM: To investigate in detail the innervation patterns of the psoas major and iliacus muscles in fetal cadavers. MATERIAL and METHODS: The innervation patterns of 94 psoas major and 94 iliacus muscles belonging to 47 fetuses (28 males, 19 females) aged between the 18th-40th gestational weeks in th...
Case Report
Patients with aneurysmal subarachnoid hemorrhage (SAH) continue to have poor functional outcome due to the occurrence of delayed cerebral ischemia (DCI). Although vasospasm represents the primary therapeutic target for mitigating DCI, DCI occurs through multifocal etiologies that involve impaired ...
Technical Note
AIM: To provide a training model for microvascular patch graft angioplasty of the common carotid arteries (CCAs) in rats. MATERIAL and METHODS: Using male Sprague-Dawley rats (n=20), an oval-shaped arterial patch 3 mm in length and 1.2 mm in width was prepared from a segment of left CCA, and a lin...
Historical Article
AIM: To present the sections allocated to hydrocephalus in the works of Ibn Hubal al-Baghd?d? and Ibn al-Quff, to include them and determine their position in the history of medicine by discussing relevant literature. MATERIAL and METHODS: A printed copy and a manuscript in İstanbul Süleymaniye Ma...
Letter to Editor