E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 33, Issue 5 (2023)
Full Metin PDF
Original Investigation
Pages: 715-721
DOI: 10.5137/1019-5149.JTN.34207-21.2
AIM: To determine the feasibility and efficacy of aura intervention in preventing the recurrence of temporal lobe epilepsy (TLE) by
observing the changes in the seizure frequency and quality of life (QOL) scale score.
MATERIAL and METHODS: A total of 160 patients will be selected from a pre-establ...
Pages: 722-730
DOI: 10.5137/1019-5149.JTN.34807-21.2
AIM: To evaluate the relationship between Golgi phosphoprotein 3 (GOLPH3) and vasculogenic mimicry (VM) in glioblastoma cells.
MATERIAL and METHODS: Glioma tissues from 40 glioma patients with different pathological grades were collected. GOLPH3 and
VM were evaluated by immunostaining in glioma ti...
Pages: 731-735
DOI: 10.5137/1019-5149.JTN.34722-21.3
AIM: To compare, and to analyze the effects of fronto-orbital band anterior displacement in the operation of premature closure of
coronal suture in infants.
MATERIAL and METHODS: A total of 31 infants with premature closure of coronal suture were randomly divided into two groups;
experimental gro...
Pages: 736-744
DOI: 10.5137/1019-5149.JTN.37875-22.2
AIM: To measure the expression of translocator protein (TSPO) in brain tissue following traumatic brain injury (TBI), and to determine
whether TSPO can predict patient outcomes.
MATERIAL and METHODS: TBI patients requiring removal of intracranial hematoma were recruited from Wujin Hospital Affilia...
Pages: 745-753
DOI: 10.5137/1019-5149.JTN.37166-21.3
Pages: 754-763
DOI: 10.5137/1019-5149.JTN.37564-22.2
AIM: To compare the outcomes of distal anterior cerebral artery (DACA) aneurysm treatment using endovascular therapy (EVT) and
surgical clipping, and to assess their risk factors.
MATERIAL and METHODS: We retrospectively sampled and analyzed 31 patients treated for ruptured Distal anterior cerebra...
Pages: 764-771
DOI: 10.5137/1019-5149.JTN.36033-21.3
AIM: To investigate the antiproliferative and apoptotic effects of S-allyl cysteine (SAC) on C6 glioblastoma cells using two- and
three-dimensional (2D and 3D) cell culture systems.
MATERIAL and METHODS: Three groups of rat glioma cell line C6 were prepared: 2D-Control, 2D-SAC, 3D-CMC-Control, and...
Pages: 772-780
DOI: 10.5137/1019-5149.JTN.41370-22.2
AIM: To understand the characterization of the ossification process both in the synostotic suture, and the adjacent parietal bone.
MATERIAL and METHODS: The surgical procedure for the 28 patients diagnosed with sagittal synostosis consisted of removing the
synostotic bone as a whole, if possible, ...
Pages: 781-789
DOI: 10.5137/1019-5149.JTN.40631-22.3
AIM: To explore the potential activity of HOXA cluster antisense RNA 2 (HOXA-AS2), a long non-coding RNA (lncRNA), in epilepsy
progression, as well as the mechanisms behind its activity.
MATERIAL and METHODS: Kainic acid (KA) was used to treat rat astroglial CTX-TNA2 cells to establish a cellular ...
Pages: 790-798
DOI: 10.5137/1019-5149.JTN.40346-22.4
AIM: To examine the morphometric properties of the vessels forming the Willis polygon (WP) in patients with type 2 diabetes mellitus
(T2DM) and hypertension (HT) and compare them with healthy individuals.
MATERIAL and METHODS: Cranial Tomography Angiography (CTA) of 168 individuals were analyzed r...
Pages: 799-803
DOI: 10.5137/1019-5149.JTN.40697-22.2
AIM: To compare tissue levels of the regulatory enzymes related to the Krebs cycle between low, and high-grade supratentorial
gliomas.
MATERIAL and METHODS: Forty patients who underwent surgery for supratentorial gliomas (19 with low-grade and 21 with
high-grade gliomas) were evaluated. The regul...
Pages: 804-810
DOI: 10.5137/1019-5149.JTN.42287-22.2
AIM: To elucidate the role of the TIR-domain-containing adaptor-inducing interferon-? (TRIF) dependent pathway in intervertebral
disc degeneration (IVD).
MATERIAL and METHODS: A total of adult male patients with low back pain (LBP) (+/- radicular pain) were further evaluated by
magnetic resonance...
Pages: 811-820
DOI: 10.5137/1019-5149.JTN.41743-22.2
AIM: To demonstrated demyelination and remyelination of the optic nerve histologically by electron microscopy in an experimental
model similar to the compression of pituitary adenomas on the optic chiasm.
MATERIAL and METHODS: The rats were fixed to a stereotaxic device under deep anesthesia, and ...
Pages: 821-827
DOI: 10.5137/1019-5149.JTN.41845-22.2
AIM: To describe the role of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in glioblastoma (GB) progression in
patients concurrently diagnosed with diabetes mellitus (DM).
MATERIAL and METHODS: Formalin-fixed paraffin-embedded (FFPE) tumor samples of 47 patients diagnosed with GB...
Pages: 828-839
DOI: 10.5137/1019-5149.JTN.42655-22.1
AIM: To present the properities of intraoperative sodium fluorescein video angiography (NaF-V) use in intracranial aneurysm surgery
and to discuss the limitations of repeated NaF-V administration.
MATERIAL and METHODS: The clinical findings and imaging results during and after surgery for patients...
Pages: 840-846
DOI: 10.5137/1019-5149.JTN.42429-22.3
AIM: To show the normal anatomy of the cerebral aqueduct, and the feasibility of the extreme anterior interhemispheric transcallosal
approach to remove tumors within the aqueduct.
MATERIAL and METHODS: This human cadaveric brain research was composed of ten formalin-fixed human brains and one
inj...
Pages: 847-854
DOI: 10.5137/1019-5149.JTN.42622-22.2
AIM: To define whether characteristics of fluorescein staining help to distinguish low grade gliomas intraoperatively.
MATERIAL and METHODS: We studied 46 patients with supratentorial newly diagnosed noncontrast-enhancing LGGs removed
by fluorescence guidance under the YELLOW 560 nm filter. Patien...
Pages: 855-861
DOI: 10.5137/1019-5149.JTN.42560-22.2
AIM: To evaluate paraoxonase (PON), total antioxidant status (TAS), total oxidant status (TOS), high-density lipoproteins (HDL), CRP,
AST, ALT, GGT, ALP levels in patients with head and multiple organ traumas.
MATERIAL and METHODS: The study included 29 male patients undergoing treatment for head ...
Pages: 862-869
DOI: 10.5137/1019-5149.JTN.41242-22.2
AIM: To observe the exposure range of a neuroendoscope through the glabellar approach and measure the anatomical parameters
to provide a basis for clinical application.
MATERIAL and METHODS: A total of 10 adult cadaveric heads fixed with formalin were dissected by stratified local anatomy and
sim...
Pages: 870-886
DOI: 10.5137/1019-5149.JTN.40460-22.3
AIM: To assess the outcomes of glioblastoma patients treated in our clinic over the last 10 years using a multimodality approach
and cutting-edge techniques.
MATERIAL and METHODS: In our study, we included 169 glioblastoma patients who were admitted to our clinic between 2009 and
2019 and receive...
Pages: 887-897
DOI: 10.5137/1019-5149.JTN.42614-22.2
AIM: To report a series of patients diagnosed with gangliogliomas (GG) in unusual locations; and to review the clinical and imaging
features as well as surgical treatment and outcomes.
MATERIAL and METHODS: A series of consecutive patients who underwent surgery for GGs at unusual locations, such a...
Pages: 898-905
DOI: 10.5137/1019-5149.JTN.43711-23.2
AIM: To evaluate the efficacy of percutaneous pain interventions in patients who previously underwent lumbar disc herniation
surgery.
MATERIAL and METHODS: We retrospectively analyzed 48 patients with persistent / recurring complaints who underwent lumbar
disc surgery (LDS) and were treated with ...
Pages: 906-911
DOI: 10.5137/1019-5149.JTN.43689-23.4
AIM: To comprehensively analyze clinical presentation, diagnosis, and management approaches of brain tumors in infants under
one year of age.
MATERIAL and METHODS: We conducted a retrospective analysis of clinical data retrieved from medical records of infants
who underwent surgical treatment for...
Case Report
Pages: 912-915
DOI: 10.5137/1019-5149.JTN.41154-22.2
Spinal intramedullary capillary hemangioma is a rare condition. Although most spinal/spinal cord hemangiomas are inborn in origin,
perinatal presentation is uncommon.
We present a neonate with an intramedullary hemangioma, born with communicating hydrocephalus and complete paraplegia.
Spinal imag...
Pages: 916-918
DOI: 10.5137/1019-5149.JTN.41381-22.2
AIM: To present the clipping of a ruptured aneurysm in the M1 segment of the right middle cerebral artery after rebleeding, which
was treated with Woven EndoBridge (WEB).
CASE REPORT: A 68-year-old male patient with known hypertension, coronary artery disease and benign prostatic hypertrophy
was ...
Letter to Editor
Pages: 919-920
DOI: 10.5137/1019-5149.JTN.44299-23.1