E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 34, Issue 5 (2024)
Full Metin PDF
Review
Neuro-Oncology
Exosome-Mediated Brain Tumor Diagnostics from Peripheral Fluids: A Review of Clinical Data
Pages: 745-754
DOI: 10.5137/1019-5149.JTN.45375-23.2
Definitive diagnoses in neuro-oncology often require invasive procedures, such as surgical biopsies to obtain tissue for histopathologic
and molecular interrogation. Patients with small lesions that may respond to nonsurgical treatments, such as chemoradiation,
may nevertheless undergo surgery wit...
Original Investigation
Neuro-Oncology
Risk Factors and the Management of Entrapped Temporal Horn following Lateral Ventricular Tumor Surgery
Pages: 755-765
DOI: 10.5137/1019-5149.JTN.36722-21.2
AIM: To investigate the risk factors and optimize the management of entrapped temporal horn (ETH) following lateral ventricular
tumor surgery.
MATERIAL and METHODS: We reviewed 41 cases of lateral ventricular tumors treated at the department of neurosurgery of our
institution between January 2012...
Spine and Peripheral Nerves
Evaluation of the Regeneration Effects of Systemically Applied Methylprednisolone and Vitamin B12 on Mental Nerve Crush Injury
Pages: 766-772
DOI: 10.5137/1019-5149.JTN.43470-23.3
AIM: To evaluate the effects of methylprednisolone and vitamin B12 injection on the regeneration of the nerves after a mental nerve
crush injury.
MATERIAL and METHODS: A total of 40 albino Wistar rats have been randomly divided into four groups: group 1 (n=10): crushlike
nerve damage was created ...
Spine and Peripheral Nerves
Effects of Surgical Timing on the Prognosis of Far Lateral Disk Herniation
Pages: 773-778
DOI: 10.5137/1019-5149.JTN.44656-23.2
AIM: To evaluate the effects of surgical timing on the prognosis in far lateral disk herniations.
MATERIAL and METHODS: We retrospectively evaluated 171 patients diagnosed with far lateral disk herniation who underwent
surgery between 2015 and 2021. Patients were divided into three groups: Those o...
Spine and Peripheral Nerves
Evaluation of the Effect of Granulocyte Colony Stimulating Factor on Spinal Fusion in a Rat Model of Spinal Surgery
Pages: 779-788
DOI: 10.5137/1019-5149.JTN.44636-23.2
AIM: To evaluate the effects of granulocyte colony stimulating factor (G-CSF) on spinal fusion through manual palpation, radiological
examinations, and histopathological analyses in a rat model.
MATERIAL and METHODS: A total of 21 rats were evaluated in this study. The rats were divided into the f...
Pediatrics
Endoscopy-Assisted Suturectomy: Can It be the Priority Choice in the Treatment of Metopic Synostosis?
Pages: 789-793
DOI: 10.5137/1019-5149.JTN.44627-23.2
AIM: To mathematically present the results of endoscopic assisted surgery in the treatment of metopic synostosis.
MATERIAL and METHODS: We present a follow-up of the stages of treatment of 43 patients with metopic synostosis who underwent
surgery in a multicenter retrospective study between 2018 a...
Spine and Peripheral Nerves
Is There a Risk of Stroke During Anterior Cervical Discectomy? A Randomized Controlled Trial
Pages: 794-801
DOI: 10.5137/1019-5149.JTN.44169-23.3
AIM: To examine the effects of different retractor techniques for anterior cervical discectomy on cerebral oxygen saturation.
MATERIAL and METHODS: In this study, a prospective comparative design was employed to examine the effects of different
retractor techniques on a cohort of 48 adult patients...
Spine and Peripheral Nerves
Finite Element Analysis of Bilateral Double Rod Constructs in Thoracolumbar Fractures
Pages: 802-808
DOI: 10.5137/1019-5149.JTN.45157-23.2
AIM: To evaluate bilateral double rod contructs in thoracolumbar fractures in a Finite Element model
MATERIAL and METHODS: A computed tomography of a 35-year old male have been chosen to create a vertebra model and 1/3
of the T12 was removed to create the burst fracture model. In model A, transped...
Neuro-Oncology
Survival and Prognostic Factors in Re-irradiation for Recurrent/Progressive Malignant Gliomas: Turkish Society of Radiation Oncology Neuro-Oncology Group, TROD 007-006 Study
Pages: 809-818
DOI: 10.5137/1019-5149.JTN.44460-23.2
AIM: To evaluate survival and prognostic factors associated with survival among patients who underwent reirradiation for recurrent/
progressive primary brain tumors.
MATERIAL and METHODS: A multicenter, retrospective study (7 centers, N=236) was conducted by the Neuro-oncology Group of
the Turkis...
Stereotactic and Functional
Repeat Microvascular Decompression for Recurrent Trigeminal Neuralgia
Pages: 819-826
DOI: 10.5137/1019-5149.JTN.45323-23.1
AIM: To review our experience with patients presenting with recurrent trigeminal neuralgia (TN) and who have undergone repeat
microvascular decompression surgery (rMVD).
MATERIAL and METHODS: This retrospective observational study was conducted at the Department of Neurosurgery at a university
ho...
Pediatrics
Investigation of the Effect of Tenoxicam on Neural Tube Defect Using Chick Embryo Model
Pages: 827-832
DOI: 10.5137/1019-5149.JTN.45237-23.2
AIM: To evaluate tenoxicam?s effects on embryonic neural tube formation to identify potential teratogenicity and determine the
underlying mechanisms leading to neural tube defects (NTDs).
MATERIAL and METHODS: This study was conducted at our University?s Neuro-embryology Laboratory. A total of 100...
Neuro-Oncology
What Happens to Serum Levels of Visinin-Like Protein-1, Caveolin-1 and Neuron-Specific Enolase after Supratentorial Glioma Resection: A Pilot Study
Pages: 833-839
DOI: 10.5137/1019-5149.JTN.44209-23.3
AIM: To observe changes in the serum levels of visinin-like protein-1 (VILIP-1), caveolin-1 (Cav-1) and neuron-specific enolase (NSE)
after glioma resection.
MATERIAL and METHODS: Consecutive 14 glioma patients with different histologic grade and 14 age and gender-matched
healthy subjects were in...
Spine and Peripheral Nerves
Surgical Treatment Results of Adult Tethered Spinal Cord Syndrome
Pages: 840-846
DOI: 10.5137/1019-5149.JTN.43843-23.6
AIM: To present symptoms and surgical results of patients operated on with the diagnosis of tethered cord syndrome (TCS) in
adulthood.
MATERIAL and METHODS: In this retrospective study, 20 patients older than 18 years were evaluated. There were 17 female and
3 male patients. Patient demographics,...
Spine and Peripheral Nerves
Assessment of Increased T2 Signal Activity in Patients with Cervical Spondylotic Myelopathy Undergoing Posterior Cervical Fusion
Pages: 847-855
DOI: 10.5137/1019-5149.JTN.45402-23.2
AIM: To compare the preoperative and postoperative increased signal intensity (ISI) outcomes of cervical spondylotic myelopathy
(CSM) patients who underwent posterior decompression and fusion, and to assess the correlation between ISI changes and
postsurgical clinical prognosis.
MATERIAL and METH...
Stereotactic and Functional
The Role of NLRP1 Inflammasome and Interleukin 1β in Experimental Neuropathic Pain Model in Rat and the Effect of Tramadol Treatment
Pages: 856-864
DOI: 10.5137/1019-5149.JTN.43768-23.3
AIM: To evaluate the effects of tramadol on inflammation by measuring NLRP1 and IL-1 beta (IL-1β) levels in an experimental
neuropathic pain model.
MATERIAL and METHODS: Sprague-Dawley rats were divided into three groups: control, chronic constriction injury (CCI), and
CCI + tramadol. Neurop...
Neuro-Oncology
A Novel Perspective to Gamma-Knife Radiosurgery for Solitary Meningiomas: Adaptability of Fast Imaging Employing Steady-State Acquisition/Constructive Interference in Steady-State Magnetic Resonance Imaging
Pages: 865-871
DOI: 10.5137/1019-5149.JTN.44895-23.2
AIM: To compare T1-weighted contrast-enhanced (T1+C) with fast imaging employing steady-state acquisition (FIESTA) magnetic
resonance imaging (MRI) sequences to protect healthy brain tissue during meningioma treatment with Gamma-Knife radiosurgery
(GKRS).
MATERIAL and METHODS: After reviewing the...
Cerebrovascular-Endovascular
Hybrid Operating Room for the Treatment of Spetzler-Martin Grade III-V Brain Arteriovenous Malformation: An Institutional Experience
Pages: 872-878
DOI: 10.5137/1019-5149.JTN.45444-23.1
AIM: To report our institutional experience of the one-stop treatment of Spetzler?Martin grade (SMG) III?V brain arteriovenous
malformations (BAVMs) in a hybrid operating room.
MATERIAL and METHODS: Clinical data obtained from all the patients with SMG III?V BAVMs who underwent one-stop treatment
...
Neurotrauma
Clinical Characteristics and Rehabilitation Results of Traumatic Brain Injury Patients Who Have Early Rehabilitation
Pages: 879-887
DOI: 10.5137/1019-5149.JTN.44265-23.3
AIM: To examine the clinical characteristics and early rehabilitation results and to investigate the relationship between rehabilitation
initiation time and rehabilitation-related outcome measurements in traumatic brain injury (TBI) patients who have early rehabilitation.
MATERIAL and METHODS: For...
General Neurosurgery and Miscellaneous-Others
Effect of External Magnetic Field on the Efficacy of ADSC Transplantation in Rats with Spinal Cord Injury
Pages: 888-897
DOI: 10.5137/1019-5149.JTN.45113-23.2
AIM: To assess the effect of intravenously injected superparamagnetic iron oxide nanoparticle (SPION)-labeled adipose-derived
stem cells (ADSCs) under an external magnetic field on the efficacy of ADSC transplantation in rats with spinal cord injury (SCI).
MATERIAL and METHODS: ADSCs were isolated...
Pages: 898-906
DOI: 10.5137/1019-5149.JTN.45091-23.2
AIM: To establish the diagnosis of basilar invagination (BI) on the basis of specific bony landmarks Klaus? index (KI), perpendicular
distance between the tip of the odontoid process and palato internal occipital protuberance (PI) line.
MATERIAL and METHODS: Forty-nine patients were analysed, who ...
Neuro-Oncology
Exogenous Ceramide Treatment Induce Death and Cytotoxicity in Glioma Cells
Pages: 907-911
DOI: 10.5137/1019-5149.JTN.44624-23.3
AIM: To evaluate the cytotoxic and proapoptotic effects of C6 ceramide on the C6 rat glioma cell line.
MATERIAL and METHODS: The C6 rat glioma cell line was evaluated. Using a confocal microscope and the appropriate software,
the cytotoxic effects of C6 ceramide were identified using 3-(4,5-dimeth...
Neuro-Oncology
Choroid Plexus Tumors of the Central Nervous System: A Review of Data with a Case of Disseminated Choroid Plexus Papilloma
Pages: 912-919
DOI: 10.5137/1019-5149.JTN.45592-23.4
AIM: To highlight the critical role of molecular profiling of choroid plexus epithelium tumors (CPTs) in guiding individualized treatment
strategies.
MATERIAL and METHODS: Histopathological diagnoses were obtained from surgically resected tumors at Centro Medico Nacional
20 de Noviembre, Mexico C...
Case Report
Neuro-Oncology
Asymptomatic Purely Intracranial Vagal Schwannoma: Clinical Case Report and Literature Review
Pages: 920-925
DOI: 10.5137/1019-5149.JTN.46250-24.2
Vagus nerve schwannoma is an infrequently occurring schwannoma, in which a distinct subtype exists wherein the tumor is
confined to the cerebellomedullary cistern without invading the jugular foramen. This unique tumor is called purely intracranial vagal
schwannoma.
In this case report, we presen...
Technical Note
General Neurosurgery and Miscellaneous-Others
Mixed Reality Assisted Navigation Guided Microsurgical Removal of Cranial Lesions
Pages: 926-938
DOI: 10.5137/1019-5149.JTN.44974-23.2
AIM: To demonstrate the possible use of mixed reality (MR) technology in neurosurgery for multiple purposes, including preoperative
planning, training, and three-dimensional (3D) navigation.
MATERIAL and METHODS: Using magnetic resonance imaging (MRI) and computed tomography (CT), 3D holographic i...
Letter to Editor
Pages: 939
DOI: 10.5137/1019-5149.JTN.46655-24.1