E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 35, Issue 4 (2025)
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Review
Pages: 527-536
DOI: 10.5137/1019-5149.JTN.46950-24.4
AIM: To systematically evaluate the existing literature regarding adjuvant or primary treatment of chronic subdural hematoma
(cSDH) with tranexamic acid (TXA).
MATERIAL and METHODS: This systematic review followed the parameters set by the Preferred Reporting Items for Systematic
Reviews and Meta...
Original Investigation
Cerebrovascular-Endovascular
The Initial Experience of Turkish Neurosurgical Stroke Centers: A National Study
Pages: 537-545
DOI: 10.5137/1019-5149.JTN.48420-25.2
AIM: To evaluate the clinical and radiological outcomes of newly established Turkish neurosurgical stroke centers , and to assess
their competency in managing acute ischemic stroke from June 2023 to June 2024.
MATERIAL and METHODS: We retrospectively analyzed data from 69 patients (mean age = 69.0...
Cerebrovascular-Endovascular
Comparison of Pre-Operative and Post-Operative Mean Transit Time Delay in Ipsilateral and Contralateral Hemispheres in Moyamoya Disease Using DSC Perfusion
Pages: 546-552
DOI: 10.5137/1019-5149.JTN.46902-24.2
AIM: To perform comparison of preoperative and postoperative mean transit time (MTT) delay in ipsilateral, and contralateral
hemispheres in Moyamoya disease using dynamic susceptibility contrast (DSC) perfusion.
MATERIAL and METHODS: Preoperative images were obtained within 1 week before surgery a...
Cerebrovascular-Endovascular
Neuroendoscopic Surgical Treatment of Hypertensive Brainstem Hemorrhage
Pages: 553-560
DOI: 10.5137/1019-5149.JTN.47812-24.2
AIM: To investigate the clinical effect of neuroendoscopic surgery on 15 patients with hypertensive brainstem hemorrhage (HBSH).
MATERIAL and METHODS: A retrospective analysis was conducted on the clinical data collected from 15 patients with HBSH
and treated with neuroendoscopy between January 20...
Cerebrovascular-Endovascular
Endovascular Occlusion of Intracranial Pial Arteriovenous Fistula: Technical Aspects
Pages: 561-569
DOI: 10.5137/1019-5149.JTN.47590-24.3
AIM: To evaluate pial arteriovenous fistulas (AVFs), focusing on the radio-anatomic architecture and contemporary endovascular
devices and techniques.
MATERIAL and METHODS: Sixteen patients with congenital pial AVFs who underwent endovascular treatment between 2002 and
2023 at a single institutio...
Cerebrovascular-Endovascular
Syringic Acid Reduces Subarachnoid Hemorrhage?Induced Oxidative Damage in Rats
Pages: 570-576
DOI: 10.5137/1019-5149.JTN.48257-24.3
AIM: To investigate the neuroprotective effects of various amounts of syringic acid (SA) on cerebral damage resulting from
experimentally induced subarachnoid hemorrhage (SAH) in rats, utilizing both histological and biochemical analyses.
MATERIAL and METHODS: In total, 40 male Wistar albino rats ...
Stereotactic and Functional
Accuracy of Deep Brain Stimulation Lead Placement Using a Cranial Robotic Guidance Platform: A Preliminary Cadaveric Study
Pages: 580-586
DOI: 10.5137/1019-5149.JTN.47419-24.2
AIM: To measure the deviation rate of a custom 3D-printed Deep Brain Stimulation (DBS) lead holder assisted electrode placements
from their intended targets, providing a benchmark for the system?s accuracy and paving the way for its use in standard DBS
workflows.
MATERIAL and METHODS: The study w...
Stereotactic and Functional
Non-Root Exit Zone Exploration during Facial Nerve Microvascular Decompression: A Discussion of the Pathogenesis in Atypical Cases of Hemifacial Spasm
Pages: 587-591
DOI: 10.5137/1019-5149.JTN.46394-24.2
AIM: To summarise atypical cases of hemifacial spasm (HFS) found during microvascular decompression (MVD), and to investigate
its pathogenesis and range of exploration.
MATERIAL and METHODS: We retrospectively analysed cases of HFS performed in our department in recent years and summarised
the in...
Stereotactic and Functional
Not to Wait Too Long After Failed Surgery for Intractable Mesial Temporal Lobe Epilepsy: Results of Reoperation at a Tertiary Hospital
Pages: 592-602
DOI: 10.5137/1019-5149.JTN.46820-24.4
AIM: To evaluate the causes and risk factors of seizure recurrence, as well as the outcomes of reoperation in patients who did not
achieve sufficient seizure control following surgery for mesial temporal lobe epilepsy (MTLE).
MATERIAL and METHODS: We retrospectively reviewed the hospital charts of...
Pediatrics
Epilepsy in Children with Myelomeningocele: A Single-Center Retrospective Cohort Study and Review of the Literature
Pages: 603-608
DOI: 10.5137/1019-5149.JTN.47393-24.2
AIM: To examine the prevalence of epilepsy and other associated cortical abnormalities in patients with Myelomeningocele (MMC),
and to present our findings along with a review of the literature.
MATERIAL and METHODS: A retrospective chart review was conducted with MMC patients followed in our pedi...
Pediatrics
Neurosurgical Management and Follow-up of Pediatric Lumbosacral Lipomas: A Single-Center Experience with 28 Patients
Pages: 609-617
DOI: 10.5137/1019-5149.JTN.46559-24.4
AIM: To evaluate the efficacy of surgical interventions for pediatric lumbosacral lipomas (LSL) by focusing on preoperative symptoms,
postoperative outcomes, and long-term prognosis.
MATERIAL and METHODS: The medical records and magnetic resonance images (MRI) of 28 pediatric patients (15 boys and...
Pediatrics
Proactive External Lumbar Drainage Use in Pediatric Idiopathic Intracranial Hypertension and Proposal of a New Treatment Algorithm
Pages: 618-626
DOI: 10.5137/1019-5149.JTN.47309-24.3
AIM: To determine if the concurrent use of external lumbar drainage (ELD) and oral medication will hasten the decrease in intracranial
pressure (ICP) and resolution of papilledema in pediatric idiopathic intracranial hypertension (IIH).
MATERIAL and METHODS: In this retrospective study, we evaluat...
Neuro-Oncology
An Ensemble Learning Approach for AI-based Classification of Paraganglioma/ Pheochromocytoma, Low Grade Glioma, and Glioblastoma Tumors
Pages: 627-635
DOI: 10.5137/1019-5149.JTN.46875-24.2
AIM: To propose a weighted vote-based ensemble classification method to classify paraganglioma/pheochromocytoma, low-grade
glioma, and glioblastoma tumors-conditions that present with similar symptoms-against other central nervous system tumors
using clinical and molecular data.
MATERIAL and METH...
Neuro-Oncology
Prediction and Analysis of Risk Factors for Lower Extremity Deep Vein Thrombosis After Craniotomy in Patients with Primary Brain Tumors: A Machine Learning Approach
Pages: 636-643
DOI: 10.5137/1019-5149.JTN.47938-24.3
AIM: To explore the risk factors associated with the occurrence of lower extremity deep vein thrombosis (DVT) after craniotomy in
patients with primary brain tumors, and to develop a predictive model using machine learning.
MATERIAL and METHODS: A prospective cohort study was conducted on 140 pati...
Neurotrauma
Thromboelastography in Patients with Chronic Subdural Hematoma: A Prospective Pilot Study
Pages: 644-651
DOI: 10.5137/1019-5149.JTN.47482-24.2
AIM: To evaluate association between chronic subdural hematoma (CSDH) and thromboelastography (TEG).
MATERIAL and METHODS: A prospective pilot study was conducted on 52 patients with CSDH. The primary outcomes were
CSDH severity, recurrence rate, and outcome. The secondary outcome was the associat...
Neuroanatomy
Anatomical Segmentation and Connectivity of the Uncinate Fasciculus
Pages: 652-660
DOI: 10.5137/1019-5149.JTN.49120-25.2
AIM: To provide a detailed anatomical segmentation of the uncinate fasciculus (UF) and to identify its cortical and subcortical
connections using complementary white matter dissection and diffusion-weighted imaging tractography techniques.
MATERIAL and METHODS: Human cadaveric cerebral hemsipheres...
General Neurosurgery and Miscellaneous-Others
Radioanatomical Assessment of the Sphenoid Ridge in Chiari Type I Malformation
Pages: 661-666
DOI: 10.5137/1019-5149.JTN.46851-24.3
AIM: To compare the sphenoid ridge (SR) morphology in patients with Chiari type I malformation (CIM) with healthy subjects.
MATERIAL and METHODS: Three dimensional (3D) computed tomography scans of 49 (25 men / 24 women) CIM patients aged
45.84±18.04 years, and 52 (26 men / 26 women) healthy subje...
Technical Note
Cerebrovascular-Endovascular
Basilar Artery Stenosis: Technical Tips to Prevent and Treat Hemorrhage during Angioplasty
Pages: 577-579
DOI: 10.5137/1019-5149.JTN.46931-24.1
To describe the strategies and techniques to improve the outcomes in intracranial hemorrhage during endovascular procedures,
a case of a 60-year-old male with symptomatic basilar artery stenosis who underwent balloon angioplasty procedure following an
iatrogenic basilar artery hemorrhage, is prese...
Case Report
Pages: 667-671
DOI: 10.5137/1019-5149.JTN.47423-24.1
Bilateral thalamic edema is commonly caused by vascular, toxic/metabolic, neoplastic, and infectious factors. However, dural
arteriovenous fistulas (DAVFs) are a relatively rare and often overlooked cause, with an incidence rate of about 8%. Tentorial
dural arteriovenous fistulas (TDAVFs) represen...
Pages: 672
DOI: 10.5137/1019-5149.JTN.46720-24.2
Traumatic spinal epidural hematoma (TSEH) is a rare condition that may cause acute spinal cord compression and lead to irreversible
neurological impairment. TSEH not only compresses the cord, but it can also worsen cervical nerve root avulsion. To our knowledge,
only five cases of combined TSEH an...