E-ISSN: 1019-5157 ISSN: 2651-5024
Original Investigation
AIM: Hyperpolarization-activated cyclic nucleotide-gated (HCN or h-channel) channels mediate hyperpolarization-activating currents in the hippocampus and neocortex. The aim of this study is to present prenatal h-channel gene expressions (HCN1 and HCN2; HCN1-Entrez-Gene ID: 84390; HCN2- Entrez Gene I...
AIM: In this report, we aim to determine the prognostic factors influencing the length of survival in patients with low-grade gliomas. MATERIAL and METHODS: In a retrospective evaluation, we have reviewed fiftythree patients who had been operated between the years of 1980 and 2006. The diagnoses...
AIM: Optimal surgical pathway for lateral ventricle tumors is still controversial. The purpose of this study is to discuss the factors that affected the preference of the surgical techniques for removing lateral ventricle tumors. MATERIAL and METHODS: 46 consecutive patients underwent operation f...
BACKGROUND: Nogo-A is a myelin-associated neurite outgrowth inhibitory protein that limits elongation of central nerve fibers, neuronal regeneration and plasticity. We investigated the effect of delivering an inhibitory peptide that neutralizes Nogo-A on neuronal recovery following mild cortical ...
OBJECTIVE: In this report, we aimed to investigate the patients that presented at our clinic complaint with diplopia due to the abducens nerve palsy and neurosurgical disease. METHODS: The study design was a retrospective review of ten cases with the abducens nerve palsy. The causes of the abduc...
OBJECTIVES: Temporal lobe epilepsy is the most common form of intractable partial epilepsy in adults with hippocampal sclerosis accounting for the majority of cases. Selective amygdalo-hippocampectomy (SEAH) is suggested as a safe and effective surgical procedure with the advantage of a better co...
BACKGROUND: Different data exist regarding long-term visual prognosis associated with suprasellar meningiomas. The aim of this study was to determine the outcome of suprasellar meningiomas with respect to short and long-term visual outcomes. METHOD: During the period of 1997 to 2006, 45 patients ...
AIM: The shunt infection rates vary from 2 to 39% among complications related to shunts used for hydrocephalus treatment. Shunt infections are reported to be more common than any other etiologies in newborn babies with myelomeningocele. MATERIAL and METHODS: In this study, we performed a retrospe...
OBJECTIVE: The aim of this presentation is to show that the sublabial transseptal transsphenoidal approach to pituitary adenomas is the least invasive anatomic route with the lowest postoperative complication rates. PATIENTS and METHOD: This study was based on a retrospective analysis of 276 pat...
Case Report
Although the first reported surgery for lumbar disc herniation was published many years ago, there still remains little agreement for the most effective treatment protocol for symptomatic cases. Many patients with extruded lumbar disc herniation require surgical intervention due to radiculopathy ...
Chondroma is a very unusual cartilagenous neoplasm of the spine. Here we are present a case of spinal chondroma with radiculopathy. A 54-year-old female patient consulted with progressive low back pain and left femoral numbness. Lumbar spinal Magnetic resonance (MR) imaging studies showed an extr...
Cerebral extra-axial metastases mimicking meningioma are extremely rare. Imaging characterictics may not always differentiate between meningioma and metastatic tumors. A 68-year-old-woman who had been operated for renal cell carcinoma 20 years ago presented with new symptoms of an intracranial ma...
Totally cystic intradural extramedullary lesions are uncommon and form a different spectrum of conditions as compared to the commonly seen intradural extramedullary tumors. Spinal schwannomas are benign tumors arising from spinal nerve root sheaths and are the most common intradural extramedullar...
Diffuse idiopathic skeletal hyperostosis (DISH) or Forestier's disease is a common disorder of unknown etiology that is characterized by ossification of the anterior longitudinal ligament of the spine and various extra-spinal ligaments. We present the case of a 54-year-old woman with progressive ...
Subfrontal schwannomas are rare lesions. They can be misdiagnosed as olfactory meningiomas or neuroblastomas. We report a case of giant schwannoma involving the anterior cranial fossa; the frontal and ethmoid sinuses and nasal cavities. The patient presented with a year-long history of increasin...
We present a case of posttraumatic infarction in the territory supplied by the lateral lenticulostriate artery after a minor head injury in a child. A 2.5-year-old child was admited to our emergency room after a head-on fall from a height of 50cm. He developed a right hemiparesis and he could not...
Ossified chronic subdural hematoma is a very rarely seen entity. We present here a 22-year-old male who had presented with severe headache consequent to brain compression caused by bifronto-parieto-temporal ossified subdural hematoma. We evaluated our method and surgical intervention in the light...
OBJECTIVES: Intracranial metastasis of ovarian tumours is rarely seen with an incidence 0.1- 5% but simultaneous diagnosis of primary undifferentiated carcinoma of the ovary and its CNS metastasis has not been published previously. MATERIAL and METHODS: A 56-year-old woman presented with headache...
Ventriculo-peritoneal shunt, one of the most common surgical procedures performed by neurosurgeons all over the world has been associated with a number of complications; the most common being infection and mechanical failure. Most of these complications tend to increase morbidity with prolonged ...
OBJECTIVE: Blister-like aneurysms are small hemispherical bulges that usually originate from the anteromedial wall of the distal internal carotid artery and cause significant subarachnoid hemorrhage. It is very important to recognize this novel lesion as a different type of aneurysm than ordinary...
Letter to Editor