E-ISSN: 1019-5157 ISSN: 2651-5024
Original Investigation
AIM: It is well known that head trauma results in damage in hippocampal and cortical areas of the brain and impairs cognitive functions. The aim of this study is to explore the neuroprotective effect of combination therapy with magnesium sulphate (MgSO4) and progesterone in the 7-days-old rat pups...
AIM: Intracranial arachnoid cysts account for 1% of all intracranial mass lesions and may require drainage if symptomatic. MATERIAL and METHODS: We retrospectively reviewed the medical records of 45 consecutive patients who underwent surgical drainage for symptomatic intracranial cysts at our inst...
AIM: Intracerebroventricular (icv) administration of beta amyloid peptide (Aβ) in rats can be used to model certain aspects of Alzheimer disease (AD).The purpose of this study was to examine the effects of intracerebroventricular Aβ (1-42) peptide injection on caspase-3 activity and expr...
AIM: The aim was to evaluate the level of interleukin 8 (IL-8), transforming growth factor β1 (TGF β1) and Nitric oxide (NO) in diffuse axonal injury (DAI) and its association to the outcome and clinical status. MATERIAL and METHODS: This cross-sectional study was conducted on 20 patient...
AIM: The dose dependent effects of alpha lipoic acid (α-LA) were investigated morphologically on rat vasospasm model. MATERIAL and METHODS: 32 rats were divided into four groups: group I=control; group II=vasospasm; group III=vasospasm +low dose (20 mg/kg) intraperitoneal α-LA administer...
AIM: To evaluate long-term postoperative facial nerve function in patients undergoing large cystic vestibular schwannomas (VSs) surgery. MATERIAL and METHODS: Surgical outcome of 36 patients with large cystic VS was retrospectively assessed, and compared with a group of 67 patients with large soli...
AIM: This study reports a technique for treating severe thoracolumbar fractures with single-stage decompression, reduction, reconstruction, and stabilization via an entirely posterior approach. MATERIAL and METHODS: The cases of 11 patients with severe traumatic thoracolumbar fractures/dislocation...
AIM: To describe a reconstructive technique using single stent for wide-necked aneurysms. MATERIAL and METHODS: This technique was described as stent-jail technique consisting of the aneurismal catheterization before the deployment of a self-expandable stent across the aneurysm neck. Following the...
AIM: We aimed to investigate the contribution of the touch imprint cytology (TIC) of core needle biopsies (CNBs) to the diagnosis in spinal lesions. MATERIAL and METHODS: Sixty cases with spinal CNB and TIC were included in the study. Hematoxylin and Eosin (H&E) and May-Grunwald- Giemsa (MGG) sta...
AIM: Comparison of long-term preoperative and postoperative clinical and radiological results for patients diagnosed with degenerative disc disease that underwent posterior dynamic stabilization. Lumbar disc degeneration is caused by a variety of factors. Disruptions in the vertebral endplate resu...
AIM: The aim of this study was to investigate retrospectively the multiple injuries prone to be missed in 432 cases. MATERIAL and METHODS: The cases were divided into two groups, i.e., whether the missed injury was found during admission or follow up. The mean ISS value, ratio of patients of cases...
AIM: To clarify the usefulness of supracondylar transjugular tubercle approach for treatment intradural lesions anterior and anterolateral to foramen magnum, in which the posterior portion of the jugular tubercle is removed extradurally through the condylar fossa with the atlantooccipital joint in...
AIM: To compare the effect of dexmedetomidine administered by intracisternal route with by intravenous route on brain tissue of rat after incomplete cerebral ischemia. MATERIAL and METHODS: Cerebral ischemia was produced by the combination of right common carotid artery occlusion and hemorrhagic ...
AIM: To evaluate the utility of 3D-magnetic resonance cisternography(MRC) of posterior cranial fossa in visualizing trigeminal neurovascular compression in patients with trigeminal neuralgia. MATERIAL and METHODS: 146 consecutive patients in the period from June 2010 to July 2011 in our institute ...
AIM: To assess the incidence, hormonal activity and postoperative follow up of the cases that are histopathologically diagnosed as atypical pituitary adenoma (APA) in our series. MATERIAL and METHODS: In this study, 13 atypical pituitary adenoma cases, by the WHO 2004 criteria, among the 146 pitui...
AIM: Stent placements for the treatment of complex internal carotid bifurcation aneurysms are not well documented yet. In this article, we reported a series of 16 such cases to evaluate the feasibility, safety and effectiveness of stent placement for these particular lesions. MATERIAL and METHODS:...
Case Report
A 65-year-old woman presented with left facial involuntary movement and facial palsy for eight years. Brain magnetic resonance image (MRI) and magnetic resonance angiography (MRA) revealed multiple vascular compression of facial nerve root exit zone (REZ). Standard retromastoid suboccipital cranie...
Schwannoma is a benign nerve sheath tumor composed of Schwann cells. A solitary schwannoma in the thorax is not rare, but a patient with Neurofibromatosis type 2 (NF2) and multiple thoracic schwannomas is extremely rare. We report the case of a 27-year-old woman with NF2 and two large schwannomas ...
Digital subtraction angiography (DSA) is the best method of evaluating carotid cavernous fistulas (CCF). DSA, however, has the disadvantage of being an invasive procedure. Computerized tomography (CT) angiography which is noninvasive, have been shown to provide more information about the size and ...
Isolated Blastomyces dermatitidis infection of the central nervous system is an uncommonly encountered entity. If left untreated it can be fatal; thus accurate diagnosis in a timely manner is critical. A 37-year-old white male presented with a severe headache. An MRI scan revealed a rightsided enh...
Jarcho Levin syndrome is a rare genetic disorder characterized by multipl vertebral and costal anomalies at birth. Jarcho Levin syndrome includes two phenotypic groups: spondylothoracic dysostosis and spondylocostal dysostosis. The prognosis of spondylothoracic dysostosis has worse than spondyloco...
Brown tumor is a bone lesion secondary to hyperparathyroidism of various etiologies. Skeletal involvement in primary hyperparathyroidism secondary to parathyroid adenoma is very uncommon and brown tumor has become extremely a rare clinical entity. Hyperparathyroidism is usually associated with hig...
Primitive neuroectodermal tumor (PNET) is presumably of neural crest origin, and cases of supratentorial PNET in adult are extremely rare. We reported a case of PNET presenting as a dumbbell-shaped tumor at the middle cranial fossa of skull base mimicking trigeminal schwannoma both clinically and ...
AIM: Spinal angiolipoma is a benign uncommon neoplasm composed of mature lipocytes admixed with abnormal blood vessels, and accounts for only 0.14-1.2% of all spinal tumors. MATERIAL and METHODS: Retrospective data analysis. RESULTS: We report two cases of a 64-year-old woman and a 65-year-old ma...
We describe a 62-year-old woman suffering from visual hallucination due to focal status epilepticus investigated by means of Magnetic Resonance Imaging (MRI), Magnetic Resonance Angiography (MRA), Electroencephalography (EEG), and 99m Technetium ethylcysteinate dimer Single Photon Emission Compute...
We describe a patient presented with sequential events of hemifacial spasm, cerebral infarction and fatal subarachnoid hemorrhage. All of them are seemingly separate entities. Radiological examination revealed that the cause was vertebrobasilar dolichoectasia (VBD) coexisting with a giant saccular...
Various complications following ventriculoperitoneal (VP) shunting have been reported but transoral protrusion of peritoneal catheter is a very rare situation. This case is the first adult with a transoral VP shunt protrusion in available literature. A 47-year-old female with pseudotumor cerebri a...
Spontaneous vertebral arteriovenous fistulae (AVF) associated with neurofibromatosis Type 1 (NF-1) is a rare occurrence in the previous reports. We presented two female NF-1 patients with a diagnosis of cervical vertebral AVF treated with endovascular approach. The fistula in the first case was su...
Remote intracranial hemorrhages after craniotomy or craniectomy may rarely develop. As the sparse literature on this phenomenon has focused on contralateral intraparenchymal and epidural clots, only seven cases of postoperative contralateral acute subdural hematomas have been reported in the liter...