E-ISSN: 1019-5157 ISSN: 2651-5024
Original Investigation
Aim: The purpose of the present study is to analyze the expression of matrix metalloproteinase-3 (MMP-3), magnetic resonance imaging (MRI) grading and histopathological alterations of the intervertebral disc (IVD) for correlations with each other and with the age, gender and low back pain duration...
Aim: Supraorbital keyhole approach provides access to the major part of the anterior circulation aneurysms. Herein, our surgical experience of supraorbital keyhole approach and its some modification have been proposed. Material and Methods: Out of a series of 76 patients harboring 80 aneurysms op...
Aim: Multilayer reconstruction of skull base using nasal pedicled mucosal flap has been widely accepted as a standard method for repairing high flow cerebrospinal fluid [CSF] leakage. In this study, we analyzed our outcome and summarized several valuable operation experiences from this technique. ...
Aim: The aim of this study was to retrospectively analyse the clinical, radiological features and surgical outcome of pineal epidermoid tumors treated at a single neurosurgical department. Material and Methods: We performed surgery on five patients with pineal region epidermoid tumors at a single...
Aim: This study aimed to investigate the effects of VNS in transient middle cerebral artery occlusion and reperfusion (MCAO/R) rat model of ischemia based on behavioral, morphological, and molecular approaches. Material and Methods: Wistar albino rats were divided into 3 groups: ischemia-reperfus...
Aim: To evaluate timing of scheduled CT-scans after burr hole trepanation for chronic subdural hematoma (cSDH). Material and Methods: 131 patients with primary cSDH were included. Scheduled CT-scans were performed after burr hole trepanation and placement of a subdural drain. The influence of CT-...
Aim: The deletion polymorphism of the angiotensin-converting enzyme (ACE) genome causes neoplastic development in several organs by increasing the angiotensin 2 (A2) formation. In this study, we aimed to identify the ACE genome insertion/deletion polymorphism in pituitary adenomas and to compare i...
Aim: To raise the awareness of the appropriate management of unusual clinical presentation of cervical disc herniation. Material and Methods: Seven patients with Brown-Sequard syndrome due to cervical disc herniation presented with Brown-Sequard syndrome had been treated surgically as one of them...
Aim: Assessment of previous vertebral fractures provides useful information to predict future fracture risk. This study aimed to determine the frequency, distribution and severity of prevalent osteoporotic vertebral fractures in postmenopausal women. Material and Methods: Data on patient characte...
Aim: Many guidelines recommend carotid endarterectomy (CEA) in symptomatic patients with carotid stenosis of greater than 70%, and carotid artery stenting (CAS) as an alternative to CEA. In our study, we evaluated the clinical characteristics of patients who underwent revascularizaton therapy. M...
Aim: The current study aims to explore the clinical characteristics of craniocerebral firearm injury and to improve the diagnosis and treatment of this condition. Material and Methods: Data from 56 patients with craniocerebral firearm injury were analyzed retrospectively for projectile types, tr...
Aim: This study was conducted with aim of determining prevalence of headache and evaluating its effects on health-related quality of life (HRQoL) in Beylikova town of Eskisehir city in the west of Turkey. Material and Methods: This study was conducted on adults aged 20 years and over aged between...
Case Report
Hydatid disease is a life-threatening parasitic infestation caused by Echinococcus granulosus. Infection with E. granulosus typically results in the formation of hydatid cysts in liver, lungs, kidney and spleen. Majority of the intracranial cysts are secondary and solitary. Multiple primary cerebr...
Rosai-Dorfman disease (RDD) is a rare but well-recognized idiopathic histioproliferative disease affecting the systemic lymph nodes. It is characterized by an unusual proliferation of histiocytic cells. Intracranial localization is a rare manifestation of RDD. The clinical and radiological differe...
Aim: Compound elevated fracture of the skull is an unusual variety of fracture of the cranial vault that has been rarely described in the currently available literature. The authors describe three such patients with post-traumatic compound elevated skull fracture. The pertinent literature is revie...
Vertebral hemangiomas are the most common tumours of the vertebral column. Generally, these tumours are asymptomatic but some patients complain of back pain and develop neurologic symptoms due to extraosseous extension. Vertebral hemangiomas can extend extradurally causing neurological impairment ...
Multiple primitive intracranial tumors with different histological characteristics are uncommon. Although coexistence of a medulloblastoma with glial tumors has been reported in children, medulloblastoma is rarely found in adults, especially those older than 40 years of age. We present an extremel...
Gangliocytoma of the pituitary gland is a rare lesion that often occurs in combination with pituitary adenomas and the exact origin is the subject of discussion. We report a rare case of an intrasellar mass of combined gangliocytoma/ pituitary adenoma coexistent with Rathke’s cleft cyst. A 5...
Pseudoaneurysms of superficial temporal artery are very rare and commonly occur as a result of blunt trauma. There are several methods for the diagnosis, but the diagnosis can be accurately made only from a history and physical examination. A 27-year-old man presented with a painless pulsatile mas...
Primary spinal melanoma (PSM) is rare and usually occurs in the cervical and thoracic regions. Here, we present a case of multiple spinal cord melanoma located at the level of cervical and upper thoracic spine in a 24-year-old male. The patient underwent a T6–T7 thoracic laminectomy and gross-tota...
Melanocytomas are rare melanocytic tumors of the central nervous system and its presence at the foramen magnum is extremely rare. We report a case of a 55-year-old male presenting with progressive quadriparesis over one year. Imaging showed a well-defined intradural extramedullary lobulated mass a...
Brain parenchyma schwannoma is a rare intracranial tumor, and especially rare in cerebellar hemisphere. In this report, a case of cerebellar schwannoma in a 52-year-old woman, was studied by computed tomography (CT), magnetic resonance image (MRI) and PET-CT. This tumor was totally removed by surg...
In moyamoya disease (MMD), subsequent aneurysm in the proximal part of the posterior communicating artery (PcomA) is extremely rare. We report the case of a middle-aged female patient with MMD, who presented with a ruptured wide-necked aneurysm at the proximal part of the developed PcomA that conv...
Aim: Chordoma is a rare, slow-growing primary malignant tumor of the axial skeleton, arising from the embryonic cells of primitive notochord. Chordomas may arise at different sites of the vertebral column simultaneously or more probably they may metastasise along the neural axis insidiously. Recur...
Ganglioglioma is one of the rare mixed neuronal glial tumors of the central nerve system. It is responsible for 0.4 – 2% of the intracranial tumors observed in infants and young matures. Its most common localization is the supratentorial region. Typically, the first symptom is epilepsy. Due ...
Ventriculostomy or external ventricular drain (EVD) placement by free-hand technique has a high malplacement rate. It is a blind procedure that often requires multiple attempts and revisions. To date, no neurological complication due to EVD malplacement has been reported in the literature. In this...
Tension pneumocephalus is a rare and life threatening complication of intracranial surgical procedures, and requires immediate recognition and surgical intervention. Tension pneumocephalus following ventriculoperitoneal shunt surgery is extremely rare and commonly seen as a delayed complication. T...
Hemorrhagic complications of acute leukemia are well described and are a common cause of mortality in these patients. However, to our knowledge, fatal intracerebral hemorrhage (ICH) as an initial presentation of acute lymphocytic leukemia (ALL) has only been reported once. We report a case of prev...
Glioblastoma is very rare in the pineal region. We report a case of glioblastoma in this region. This is the 18th case of primary glioblastoma in the pineal region and the second case that survived over two years according the literature. A 60-year-old man admitted with headache and ataxia that co...
Eosinophilic granuloma is a rare disease belonging to the Langerhans’ cell histiocytosis group. It accounts for only 1% of all tumor-like lesions of bone. A 6-year-old girl presented with proptosis, and a mass and pain in her right eye. Cranial computerized tomography and magnetic resonance ...