E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 26, Issue 4 (2016)
Full Metin PDF
Review
Pages: 465-474
DOI: 10.5137/1019-5149.JTN.15773-15.0
Hemodynamic changes during pregnancy may favor the formation and rupture of intracranial aneurysms. Despite this risk, guidelines
for managing intracranial aneurysms during pregnancy have not been clearly defined. The objective of this review is to describe the
treatment options for pregnant women...
Original Investigation
Pages: 475-483
DOI: 10.5137/1019-5149.JTN.14534-15.0
AIM: Insular gliomas have traditionally been approached through variations of large frontotemporal craniotomies exposing much
of the Sylvian fissure. Due to the importance of many structures exposed by such an approach, a less-invasive approach to these
lesions is a viable alternative for resectio...
Pages: 484-490
DOI: 10.5137/1019-5149.JTN.16552-15.1
AIM: Glioblastoma (GBM) is the most common and the most aggressive primary brain tumor with poor prognosis. We aimed to
evaluate the association between immunohistochemical expression of survivin and angiogenic parameters (microvessel density and
vascular pattern) in patients who underwent surgery...
Pages: 491-499
DOI: 10.5137/1019-5149.JTN.13789-14.0
AIM: To present a new simple disposable tubular retractor which provides fully endoscopic resections of the intraaxial brain lesions.
MATERIAL and METHODS: A total of 13 patients underwent surgical resection of an intraaxial brain lesion larger than 3 cm with
a fully endoscopic approach using the ...
Pages: 500-512
DOI: 10.5137/1019-5149.JTN.15192-15.1
AIM: We have applied diffusion tensor imaging (DTI) to interrogate microstructural changes in white matter integrity in a widely used
middle cerebral artery occlusion (MCAO) model of cerebral ischemia.
MATERIAL and METHODS: We performed ex vivo DTI 35 days after 60 minutes transient focal ischemia...
Pages: 513-517
DOI: 10.5137/1019-5149.JTN.6570-12.1
AIM: To report the angiographic and clinical results achieved in endovascular treatment of ruptured posterior circulation cerebral
aneurysms over a 3-year period.
MATERIAL and METHODS: A retrospective analysis of 45 patients was performed between June 2008 and June 2011. Clinical
follow-up was ac...
Pages: 518-524
DOI: 10.5137/1019-5149.JTN.7691-12.1
AIM: To present our experience on transarterial treatment of dural arteriovenous fistulas (DAVFs) with ONYX in adult patients.
MATERIAL and METHODS: Between March 2008 and November 2012, 27 adult patients with DAVFs treated by transarterial
ONYX embolization were included. Clinical data, including...
Pages: 525-532
DOI: 10.5137/1019-5149.JTN.14759-15.0
AIM: We evaluated the procedural outcomes of intracranial aneurysm treatment with the Silk device and its relation with operator
experience. We also detailed some technical points we learned throughout our experience.
MATERIAL and METHODS: One hundred and six consecutive patients with intracranial...
Pages: 533-537
DOI: 10.5137/1019-5149.JTN.14760-15.0
AIM: To report patient and procedure-related factors affecting the angiographic and clinical outcome in patients treated with the
Silk device.
MATERIAL and METHODS: All patients with intracranial aneurysms in whom treatment was attempted with the Silk flow diverter
by our neurovascular team betwe...
Pages: 538-544
DOI: 10.5137/1019-5149.JTN.13650-15.1
AIM: To explore the effect of simvastatin on proliferation of vascular smooth muscle cells (VSMCs) during delayed cerebral
vasospasm (dCVS) after subarachnoid hemorrhage (SAH).
MATERIAL and METHODS: Thirty-six male New Zealand White rabbits were randomly divided into three groups: 1) Control group...
Pages: 545-549
DOI: 10.5137/1019-5149.JTN.14408-15.1
AIM: We set forth to identify predictors of symptomatic vasospasm in patients with subarachnoid hemorrhage (SAH).
MATERIAL and METHODS: We used multivariate logistic regression analysis of the prospective, hospital based, single center
register of the Department of Neurosurgery, University of Debr...
Pages: 550-555
DOI: 10.5137/1019-5149.JTN.14195-15.3
AIM: This study was designed to elucidate the neuroprotective effect of resveratrol in a mouse model of bilateral common carotid
artery occlusion (BCCAO).
MATERIAL and METHODS: Sixty male C57BL/6 mice, weighing 20–24 g, were used in our experiments. The mice were randomly
assigned into thre...
Pages: 556-563
DOI: 10.5137/1019-5149.JTN.12668-14.3
AIM: Because of the need for effective method to determine the severity of head trauma, the importance of biomarkers is recognized
recently. This study aims to analyze the values of sera levels of some biomarkers and the relation with their tissue levels in acute
head injury.
MATERIAL and METHODS...
Pages: 564-567
DOI: 10.5137/1019-5149.JTN.9187-13.0
AIM: This study was designed to determine the anatomic position of the asterion and the relationship between the asterion and the
transverse sigmoid sinus junction (TSSJ) in a Chinese cohort.
MATERIAL and METHODS: Venous computed tomography (CT) angiography was performed in 32 patients to simultan...
Pages: 568-573
DOI: 10.5137/1019-5149.JTN.12293-14.1
AIM: Cadaveric studies have a great impact on neuroanatomy learning. Cadaver preparation may take a lot of effort, especially at
the phase of intravascular color filling. The authors describe their silicone dye technique and a novel mixture which is self-curing,
quick to prepare and easy to inject...
Pages: 574-581
DOI: 10.5137/1019-5149.JTN.11400-14.2
AIM: To investigate the application of neuronavigation in the implantation of depth electrodes in patients with epilepsy.
MATERIAL and METHODS: Thirty-six patients with epilepsy who were implanted with depth electrodes using neuronavigation
were assessed for accuracy of implantation and associated...
Pages: 582-585
DOI: 10.5137/1019-5149.JTN.7800-13.1
AIM: To investigate the effect of intrathecal anti-fibroblast growth factor-2 (FGF-2) antibodies on the mechanical allodynia and
activation of spinal cord astrocytes in a rat model of neuropathic pain.
MATERIAL and METHODS: Forty male Sprague-Dawley rats were randomly divided into 4 groups (Each g...
Pages: 586-594
DOI: 10.5137/1019-5149.JTN.14518-15.3
AIM: To demonstrate the effect of glatiramer acetate (GA) in chick embryos on neural tube (NT) development, and to explore its
effects of Foxp1, apoptosis, and N-cadherin.
MATERIAL and METHODS: One hundred fertile, specific pathogen free eggs were divided into 5 groups for this study. The eggshell...
Pages: 595-600
DOI: 10.5137/1019-5149.JTN.13206-14.0
AIM: Failure of surgery for lumbar disc herniation (LDH) can be commonly caused by recurrence. There are many debates regarding
the risk factors of recurrent LDH (rLDH) and it is very difficult to define them because many clinical and complicated biomechanical
parameters are involved. The purpose ...
Pages: 601-607
DOI: 10.5137/1019-5149.JTN.14348-15.1
AIM: To describe the demographics, clinical and radiologic presentation, surgical considerations, and clinical outcomes associated
with spinal osteoblastoma.
MATERIAL and METHODS: A spinal tumor database of 522 patients treated surgically at a single institution between January
2002 and June 2012...
Pages: 608-614
DOI: 10.5137/1019-5149.JTN.12294-14.1
AIM: To evaluate the efficacy, feasibility and safety of a percutaneous anatomical vertebral body reduction for the treatment of VCF
(vertebral compression fracture) linked to malignancy. Vertebroplasty and percutaneous kyphoplasty have played essential roles in
the treatment of painful vertebral ...
Pages: 615-621
DOI: 10.5137/1019-5149.JTN.13884-14.2
AIM: To analyze retrospectively the surgical management of reducible atlantoaxial dislocation (AAD), basilar invagination (BI) and
Chiari malformation (CHM) with syringomyelia through a single-stage posterior approach.
MATERIAL and METHODS: Forty-three patients with reducible AAD, BI and CHM with ...
Pages: 622-631
DOI: 10.5137/1019-5149.JTN.13210-14.1
AIM: To evaluate the neuroprotective effects of adalimumab in an experimental spinal cord injury model and compare them with
those of the widely-used methylprednisolone.
MATERIAL and METHODS: Forty male Wistar rats were divided into 5 as the sham, trauma, adalimumab, methylprednisolone,
and adali...
Case Report
Pages: 632-634
DOI: 10.5137/1019-5149.JTN.8140-13.3
When tinnitus is pulse-synchronous, a vascular etiology is suggested. We present a case of persistent and troublesome pulsatile
tinnitus caused by a transverse-sigmoid sinus diverticulum that was endovascularly treated with stent-assisted coiling. A 39-yearold
woman presented with a 4-year history...
Pages: 635-642
DOI: 10.5137/1019-5149.JTN.8476-13.0
In patients affected by malignant tumors, spinal column metastases are frequent. The incidence varies between 30% and 70%.
Lung cancer is the second most frequent cancer invading the spine in women, following breast cancer. All patients are under risk of
symptomatic spinal cord compression. The pr...
Pages: 643-645
DOI: 10.5137/1019-5149.JTN.8574-13.0
Fahr’s Syndrome is characterized by the presence of intracerebral, bilateral and symmetrical calcifications located in bilateral
basal ganglia, thalamus, and cerebellum. The etiology is not exactly known. The authors reported a very rare case who had Fahr’s
Syndrome and intracerebral a...
Pages: 646-652
DOI: 10.5137/1019-5149.JTN.15271-15.1
While several approaches have been suggested for performing a transthoracic corpectomy of the thoracolumbar spine, the steep
learning curve and high risk of operative morbidity often dissuades its use clinically. As a result, posterior approaches have been
more frequently used, though transthoraci...