E-ISSN: 1019-5157
ISSN: 2651-5024
Research
Predictive Value of Cerebrospinal Fluid Hydrodynamic Parameters for Short-term Postoperative Outcomes in Patients with Syringomyelia
Li Hao✉ ,
Liu Yong ,
Cui Zhiqiang
DOI: 10.5137/1019-5149.JTN.49969-25.2
Article in Press
Corresponding Author:
Li Hao (lihao1285@126.com)
Abstract
Aim
To evaluate the predictive value of cerebrospinal fluid (CSF) hydrodynamic parameters for short-term postoperative outcomes in patients with syringomyelia (SM).
Material and Methods
200 SM patients, including both Chiari I malformationrelated and non-Chiari cases, treated at our hospital from February 2023 to December 2024 were enrolled in the study, and they were divided into a good recovery group and a poor recovery group based on short-term postoperative efficacy. The maximum CSF systolic velocity (MSV), maximum CSF diastolic velocity (MDV), and other potential factors influencing postoperative outcomes were compared between the two groups. Logistic regression analysis was conducted to identify determinants of surgical efficacy. Receiver operating characteristic (ROC) curves were plotted to assess the predictive value of MSV and MDV for poor short-term postoperative outcomes, and the Kappa consistency test was utilized to evaluate the combined predictive performance of MSV and MDV.
Results
Of the patients, 169 were classified into the good recovery group, and 31 into the poor recovery group. The poor recovery group had a longer disease course, more comorbidities, and higher MSV and MDV (P < 0.05). MSV and MDV were independent predictors of poor outcomes. Cutoff values were 3.18 cm/s (MSV) and 3.12 cm/s (MDV), with AUCs of 0.772 and 0.719, respectively. Combined prediction using MSV and MDV showed strong agreement (Kappa = 0.837, P < 0.05).
Conclusion
MSV and MDV are valuable predictors of poor short-term surgical outcomes in SM patients and can guide early risk stratification.
To evaluate the predictive value of cerebrospinal fluid (CSF) hydrodynamic parameters for short-term postoperative outcomes in patients with syringomyelia (SM).
Material and Methods
200 SM patients, including both Chiari I malformationrelated and non-Chiari cases, treated at our hospital from February 2023 to December 2024 were enrolled in the study, and they were divided into a good recovery group and a poor recovery group based on short-term postoperative efficacy. The maximum CSF systolic velocity (MSV), maximum CSF diastolic velocity (MDV), and other potential factors influencing postoperative outcomes were compared between the two groups. Logistic regression analysis was conducted to identify determinants of surgical efficacy. Receiver operating characteristic (ROC) curves were plotted to assess the predictive value of MSV and MDV for poor short-term postoperative outcomes, and the Kappa consistency test was utilized to evaluate the combined predictive performance of MSV and MDV.
Results
Of the patients, 169 were classified into the good recovery group, and 31 into the poor recovery group. The poor recovery group had a longer disease course, more comorbidities, and higher MSV and MDV (P < 0.05). MSV and MDV were independent predictors of poor outcomes. Cutoff values were 3.18 cm/s (MSV) and 3.12 cm/s (MDV), with AUCs of 0.772 and 0.719, respectively. Combined prediction using MSV and MDV showed strong agreement (Kappa = 0.837, P < 0.05).
Conclusion
MSV and MDV are valuable predictors of poor short-term surgical outcomes in SM patients and can guide early risk stratification.
Keywords
cerebrospinal fluid
hydrodynamic parameters
syringomyelia
short-term outcomes
prediction