E-ISSN: 1019-5157 ISSN: 2651-5024
Review
AIM: To conduct an updated systematic review and meta-analysis to compare the efficacy and safety between total disc replacement (TDR) and fusion surgery for lumbar degenerative disc disease (LDDD). MATERIAL and METHODS: We comprehensively searched meta-analyses comparing TDR with fusion through t...
Original Investigation
AIM: To evaluate the over expression of Glucose-regulated protein 78 kda (GRP78) in recurrent glioblastoma multiforme (GBM) and explore its chemoresatance. MATERIAL and METHODS: Western blot analysis and real-time PCR were done to detect the expression of GRP78 in GBM tissues. RESULTS: It was det...
AIM: To learn how rat primary somatosensory cortex (pSSC) responses to the loss of inputs from hind-paw, using fMRI of an inferior magnetic power (1.5 Tesla) with special designed high-powered rat coil. MATERIAL and METHODS: Ten adult male Sprague-Dawley rats were enrolled in this study. The rats ...
AIM: To evaluate the efficacy of using a neuronavigation system for demonstrating the relationship between the basilar artery (BA) and ventricular floor during endoscopic third ventriculostomy (ETV). MATERIAL and METHODS: Records of 28 patients (16 females and 12 males) diagnosed with obstructive ...
AIM: To investigate the safety and efficacy of Derivo® embolisation device (DED), a new-generation flow diverter designed to treat cerebrovascular aneurysms, and its long-term clinical outcomes. MATERIAL and METHODS: In total, 146 patients with 182 aneurysms were treated with DED. The mean age of...
AIM: To evaluate whether there is any difference in voice quality between patients who were operated via microscopic and endoscopic approaches for pituitary adenomas. MATERIAL and METHODS: The study group consisted of 59 patients and 30 healthy volunteers. They were all males and divided into thr...
AIM: To investigate predictive factors for a favorable outcome from subthalamic nucleus-deep brain stimulation (STN-DBS) in Parkinson’s disease (PD) and whether low serum vitamin B12 (vB12) levels can predict an unfavorable outcome. MATERIAL and METHODS: Thirty-nine patients with PD who underwen...
AIM: To predict the overall survival (OS) and the cancer-specific survival (CSS) of patients with high-grade glioma (HGG) using nomograms and the surveillance, epidemiology, and end results (SEER) database (2000-2013). MATERIAL and METHODS: A total of 3706 patients with high-grade glioma were iden...
AIM: To investigate the neuroprotective effect of a N-methyl-D-aspartate (NMDA) receptor antagonist (amantadine) in an experimental spinal cord injury (SCI) model. MATERIAL and METHODS: Thirty male Sprague–Dawley rats were divided into three groups: control (I), SCI (II), and SCI + amantadine (...
AIM: To identify the effects of computer assisted training schemes provided to patients who have undergone surgical intervention for lumbar disc herniation on their level of knowledge, level of anxiety, problems experienced after discharge, and level of functional incapacity. MATERIAL and METHODS...
AIM: To explore the anatomic features of the neural foramen in particularly at the T12-L1 level in order to assess reveal the safety and efficiency of the endoscopic transforaminal approach for paramedian and foraminal disc herniations at this level. MATERIAL and METHODS: The study included 15 fre...
AIM: To report the surgical outcomes in patients with trigeminal neuralgia (TN) who underwent microvascular decompression (MVD) with superior petrosal vein sacrification. MATERIAL and METHODS: Data from 63 patients, whose information was obtained from a group of 113 patients who underwent surgery...
AIM: To investigate the incidence, risk factors, and recovery of patients with meralgia paresthetica (MP) following posterior spine surgery. MATERIAL and METHODS: Patients who underwent posterior spine surgeries in prone position at the authors’ clinics were included in this study. Patients wit...
AIM: To determine whether the timing of shunt placement affects shunt infection rate in hydrocephalus associated with myelomeningocele (MMC). MATERIAL and METHODS: The cases of 67 consecutive patients who underwent MMC repair and ventriculoperitoneal (VP) shunt placement between 2010 and 2017 wer...
AIM: To evaluate the changes in the pressure values of the ulnar nerve after in-situ decompression and anterior subcutaneous transposition of the ulnar nerve. MATERIAL and METHODS: The ulnar nerve was released in the postcondylar groove. An ultrathin (100 lm) force transducer was embedded between...
AIM: To determine the expression profile of miRNA-199a-5p in intervertebral disc degeneration (IDD) and its correlation to the grade of IDD. MATERIAL and METHODS: This case-controlled study was conducted during a 6-month period from 2017 to 2018 in two university hospitals in Shiraz, Iran. We inc...
AIM: To determine the feasibility and efficacy of full endoscopic interlaminar discectomy (FEID) for recurrent disc herniation. MATERIAL and METHODS: This retrospective single-center study included 60 patients. Among them, 36 who previously had microdiscectomy underwent revisional FEID (MD group),...
AIM: To investigate the utility of two different interpositional materials (muscle graft vs. fascia flap) for preventing the osseous reunion of skull bone defect including the coronal suture line in rats. MATERIAL and METHODS: A total of 32 male Sprague-Dawley rats were divided into 2 groups (n=16...
AIM:To evaluate the long-term outcomes and prognostic variables in a surgical cohort of pediatric meningiomas treated in a single institution. MATERIAL and METHODS: Medical records and follow-up notes of 23 pediatric patients aged 3) during the last follow-up assessment. Ten patients (43.5%) had ...
Case Report
Simultaneous presence of the persistent primitive trigeminal artery and so-called intermediate communicating artery was discovered in a 77-year-old cadaver autopsied due to the myocardial infarction. Many vascular variants and abnormalities such as aplasia of the right vertebral artery (VA), prese...
Ventriculo-gallblader shunt is very rarely used in the treatment of hydrocephalus. A 44-year-old male with ventriculoatrial shunt dysfunction was evaluated. His ventriculoatrial shunt was not working. His medical history revealed that his hydrocephalus was treated five times by venrtriculoperitone...
The diagnostic spectrum for scalp lesions is extensive and comprises either benign or malignant features. Cornu cutaneum (CC) is a well-recognized condition; however, its origin and natural course are not always obvious. We present the case of a 78-year-old male patient who was diagnosed with intr...
Cavernous angiomas (cavernomas) are vascular malformations of the brain characterized by abnormal capillaries. Ventricular cavernomas are considered rare; however, an extremely unusual topography is the septum pellucidum, with only five reported cases in the English literature. These malformations...
Technical Note
AIM: To present the surgical planning, manufacturing and implantation of an individualized 3D-printed prosthesis for cervicothoracic reconstruction in a six-level recurrent chordoma. MATERIAL and METHODS: A 40-year-old female patient with recurrent cervicothoracic chordoma was admitted in our cent...
Letter to Editor