E-ISSN: 1019-5157 ISSN: 2651-5024
Original Investigation
AIM: To evaluate the feasibility and long-term clinical results of combined surgical resection and high-dose methotrexate (HD-MTX) chemotherapy for primary central nervous system lymphoma (PCNSL) of the brain. MATERIAL and METHODS: Fifty-eight patients were diagnosed with PCNSL by histopathologica...
AIM: To evaluate diffuse axonal injury (DAI) patients according to DAI stage to identify risk factors that may affect clinical outcome. MATERIAL and METHODS: A total of 992 traumatic brain injury (TBI) patients visited our hospital between 2011 and 2016. Thirtyseven patients diagnosed with DAI wer...
AIM: To describe a deep convolutional generative adversarial networks (DCGAN) model which learns normal brain MRI from normal subjects than finds distortions such as a glioma from a test subject while performing a segmentation at the same time. MATERIAL and METHODS: MRIs of 300 healthy subjects we...
AIM: To investigate the morphology of the lower lumbar intervertebral foramina through using a digital three-dimensional (3D) simulation model to guide the endoscope through the intervertebral foramina. MATERIAL and METHODS: Individuals without disease affecting the lumbar vertebrae underwent comp...
AIM: To develop a scale in Turkish language for evaluating the surgical specialty residents? perceptions of educational climate in the operating room, with an emphasis on learning in the operating suite and planning the relevant change for improved and standardized training. MATERIAL and METHODS:...
AIM: To examine the variations in number, size, and shape of foramina transversaria (FTs) of cervical vertebrae, and to discuss their clinical importance. MATERIAL and METHODS: The FTs of 200 dry cervical vertebrae (C3?C7) from 40 spines were studied for the presence of variations in their number...
AIM: To clarify perfusion differences, and to determine whether children and adults respond similarly to surgical prevention and how brain perfusion stages before surgery predict outcomes in ischaemic moyamoya disease (MMD) in children and adults. MATERIAL and METHODS: A total of 355 patients with...
AIM: To identify the risk factors for aneurysmal intra-procedural rupture (IPR) of intracranial aneurysms suring endovascular treatment, and to discuss its management and outcomes. MATERIAL and METHODS: A total of 106 patients with cerebral aneurysm who have undergone endovascular treatment (EVT) ...
AIM: To compare the diffusion properties of brain metastases as imaging biomarkers in various types of tumours, to determine their histology and origin. MATERIAL and METHODS: Magnetic Resonance Imaging (MRI) and diffusion-weighted imaging (DWI) were used to retrospectively study the data of 143 p...
AIM: To compare an antiplatelet-preparation group with a no-preparation group to evaluate the effect of the antiplatelet preparation on procedural thromboembolism during endovascular thrombectomy (EVT) with diffusion-weighted imaging (DWI), retrospectively. MATERIAL and METHODS: From January 2017 ...
AIM: To compare the effects of sevoflurane and propofol anesthesia on perioperative cerebral oxygenation in patients undergoing carotid endarterectomy (CEA) under general anesthesia by using near-infrared spectroscopy (NIRS) monitoring. MATERIAL and METHODS: Institutional approval was obtained, an...
AIM: To reveal the efficiency of our surgical approach algorithm in patients with thoracolumbar pyogenic spondylodiscitis based on the involvement of anatomical structure. MATERIAL and METHODS: Data of patients who underwent debridement or stabilization surgery for thoracolumbar pyogenic spondylo...
AIM: To histopathologically evaluate and compare bone morphogenetic protein (BMP)-2, vascular endothelial growth factor (VEGF), and vitamin D receptor (VDR) levels in the ligamentum flavum (LF) of patients with lumbar spinal stenosis (LSS) and lumbar disc herniation (LDH). MATERIAL and METHODS: S...
AIM: To investigate and compare the efficacy and safety of vagus nerve stimulation (VNS) therapy in different types of epilepsy. MATERIAL and METHODS: Patients, who were implanted with VNS between the years 2005 and 2020, were retrospectively included in the study. Age, gender, age at seizure onse...
AIM: To compare external ventricular drain-related infection (EVD-RI) rates of two Academic Medical Centers in Turkey and the US in order to determine the key factors. MATERIAL and METHODS: We performed an observational retrospective cohort study to compare the EVD-RI rates between two hospitals ...
AIM: To present a series of medically refractory focal epilepsy patients with multiple or eloquent epileptogenic zones (EZs) in whom a responsive neurostimulation (RNS) system was used as a complementary modality to surgical resection. RNS was also used as a diagnostic tool to monitor long-term ep...
AIM: To develop an approach for atrial application of ventriculoatrial (VA) shunts after revealing the venous anatomy with facial and cervical anatomical dissections. MATERIAL and METHODS: Five cephalic cadavers were used in the study. Facial and cervical regions of the cephalic cadavers were exa...
AIM: To demonstrate the possibility of revision screw placement to the atlas, as well as define the safety zones and orientation angles. MATERIAL and METHODS: This retrospective study analysed the records of four patients who were operated for AAI earlier. Because they needed revision of Atlas sc...
AIM: To evaluate the clinical features, treatment approaches, and outcomes of glial tumors in children. MATERIAL and METHODS: Files (2006 to 2020) of children diagnosed with glial tumors and followed-up were reviewed retrospectively. Information regarding demographic and clinical characteristics, ...
AIM: To discuss seizure outcomes of patients with invasive electroencephalography (EEG) monitorization (IEM) following their epilepsy surgery at our centre. MATERIAL and METHODS: Forty-seven patients suffering from refractory epilepsy and who were evaluated by invasive EEG were included in this r...
AIM: To evaluate the effect of various temperatures and durations of radiofrequency thermocoagulation (RFT) for the treatment of low back pain that is caused by facet joints. MATERIAL and METHODS: This is a randomized controlled, double-blind study. Patients diagnosed with facet syndrome were ran...
Case Report
Mitochondrial encephalomyopathy, lactic acidosis, and recurrent stroke-like episodes (MELAS) syndrome is a rare but one of the most common maternally inherited multisystem disorder. Although patients with MELAS present a variable clinical profile, strokelike lesions have been detected in 90% of ca...
AIM: To discuss the use of flow modulation in treating ruptured aneurysms of the proximal segment of the anterior cerebral artery (A1 aneurysms). A1 aneurysms are rare, constituting approximately 1% of all intracranial aneurysms. CASE REPORT: We report a left A1 aneurysm with a wide neck and small...
Intermediate-grade meningeal melanocytoma (IGM) is a rare tumor that has not been reported in children so far. It is speculated to have more aggressive clinical behavior with undefined best management options. In this study, we present a 19-month-old girl as the first case with IGM in English lite...
Letter to Editor