E-ISSN: 1019-5157
ISSN: 2651-5024
Vol. 36, Issue 2 (2026)
Full Metin PDF
Original Investigation
Review
A Comparative Study of Large Language Models in Turkish Neurosurgery Education Using a Mock Neurosurgery Board Examination
Pages: 183-199
DOI: 10.5137/1019-5149.JTN.50196-25.3
AIM: To evaluate Deepseek-R1, Gemini-2.0 Pro, ChatGPT-o3-mini-high, and GPT-4.5 on a mock neurosurgery board exam to assess
their accuracy and educational value.
MATERIAL and METHODS: We created a 50-question mock neurosurgery board examination and administered it to three major
large language mo...
Review
Beyond Human 'Eyes' in Neurosurgical Exams: Success of Artificial Intelligence (ChatGPT-4o, Grok, and Gemini) in the Image-Based Questions of Turkish Neurosurgical Society Proficiency Board Exams
Pages: 200-210
DOI: 10.5137/1019-5149.JTN.49058-25.2
AIM: To evaluate the impact of generative artificial intelligence and large language models (LLMs) on medical training and
neurosurgical education, specifically focusing on their emerging capabilities in image interpretation.
MATERIAL and METHODS: This study evaluated the performance of three majo...
Review
From Presentation to Publication: Publication Rates of Abstracts Presented at the Meetings of Two Neurosurgical Societies in Türkiye
Pages: 211-217
DOI: 10.5137/1019-5149.JTN.48850-25.2
AIM: To assess the overall trends in scientific dissemination at neurosurgery meetings organized by the Turkish Neurosurgical
Society (TNS) and the Society of Surgery of the Nervous System (SSNS), two major neurosurgical societies in Turkey.
MATERIAL and METHODS: We reviewed 2,696 abstracts presen...
Erratum
Affordable Excellence: A Meta-Analysis on the Efficacy of Topical Tranexamic Acid in Reducing Blood Loss in Thoracolumbar Spinal Surgery
Pages: 218-228
DOI: 10.5137/1019-5149.JTN.48875-25.2
AIM: To evaluate the efficacy and safety of topical tranexamic acid (tTXA) in thoracolumbar fusion surgery.
MATERIAL and METHODS: A systematic review was conducted per PRISMA guidelines. Studies from January 1970 to August
2024 were retrieved from PubMed, Cochrane, EMBASE, Medline, and Google Scho...
Erratum
Hemostasis Versus Immunosuppression in Preventing Postlaminectomy Epidural Fibrosis: An Experimental Study in Rats
Pages: 229-236
DOI: 10.5137/1019-5149.JTN.48680-25.2
AIM: To compare haemostasis induced with tranexamic acid (TXA) and immunosuppression induced with infliximab (INF) as
strategies to reduce epidural fibrosis (EF) in rat laminectomy model.
MATERIAL and METHODS: Twenty-one male Sprague?Dawley rats were randomly assigned into control group (no treatm...
Erratum
Complications of Biportal Endoscopic Surgery for Lumbar Pathologies: Retrospective Analysis of 374 Cases
Pages: 237-245
DOI: 10.5137/1019-5149.JTN.48431-25.3
AIM: To evaluate the complications associated with Unilateral Biportal Endoscopy (UBE) in spinal surgery, highlighting the risks and
outcomes of this minimally invasive approach.
MATERIAL and METHODS: A retrospective analysis was conducted on 374 patients who underwent UBE at three centers from
2...
Erratum
Finite Element Analysis of Mechanical Stress Distribution in Titanium and PEEK Rod Constructs for Isthmic L5-S1 Spondylolisthesis
Pages: 246-253
DOI: 10.5137/1019-5149.JTN.49191-25.2
AIM: To compare the biomechanical behavior of titanium and polyetheretherketone (PEEK) rods using finite element analysis (FEA)
in a Grade I L5-S1 isthmic spondylolisthesis model.
MATERIAL and METHODS: An anatomically accurate 3D finite element model of the L3?S1 spine was created from CT data of ...
Erratum
Effects of Caudal Epidural Pethidine on Pain Control and Early Mobilization after Posterior Spinal Instrumentation: A Randomized Controlled Trial
Pages: 254-263
DOI: 10.5137/1019-5149.JTN.48568-25.3
AIM: To evaluate the effects of administering pethidine (also known as meperidine), a long-acting narcotic analgesic, via the
caudal epidural route at the conclusion of posterior lumbar instrumentation (PLI) surgery on postoperative pain control, and early
mobilization of patients.
MATERIAL and M...
Erratum
Comparison of the Effects of Amantadine, Methylprednisolone and Nimodipine in Sciatic Nerve Crush Injury
Pages: 264-274
DOI: 10.5137/1019-5149.JTN.48165-24.2
AIM: To assess the therapeutic effects of methylprednisolone, nimodipine, and amantadine on peripheral nerve injury using a rat sciatic nerve compression model, simulating potential treatments for humans.
MATERIAL and METHODS: A total of 36 adult male Wistar albino rats were divided into five groups...
Article With VideoClip
Evaluation of the First Cervical Vertebra Anatomy for Screw Fixation
Pages: 275-280
DOI: 10.5137/1019-5149.JTN.48751-25.4
AIM: To conduct a morphometrical analysis of the atlas to facilitate the development of atlas-related treatment methods and
demonstrate the variations in atlas anatomy to aid surgical approaches and reduce complications.
MATERIAL and METHODS: The present study was conducted on 58 dry human atlas v...
Letter to Editor
Impact of DNA Methylation Profiling on Central Nervous System Tumor Diagnosis and Management: A Pediatric Cohort Study from Türkiye
Pages: 281-293
DOI: 10.5137/1019-5149.JTN.50069-25.2
AIM: To present a single-center experience, and to highlight the urgent need for multi-institutional collaboration in Türkiye and
surrounding regions lacking access to methylation platforms, with the aim of enhancing diagnostic precision and neuropathological
practice.
MATERIAL and METHODS: All p...
Turkish Neuro -Excursion
Acute Subdural Hematoma: Evaluation of Predictive Factors and Efficacy of Various Surgical Approaches on Prognosis
Pages: 302-309
DOI: 10.5137/1019-5149.JTN.48038-24.3
AIM: To examine the parameters influencing prognosis, and the effectiveness of surgical techniques in patients aged over 65 years
with acute subdural hematoma (ASH).
MATERIAL and METHODS: From 2017 to 2023, a retrospective evaluation was conducted on 62 individuals admitted to the
emergency depar...
Clinical Quiz
Shape Analysis of the Corpus Callosum in Pediatric Hydrocephalus: A Comparison Between Cases with and without Shunt Revision Surgery
Pages: 310-315
DOI: 10.5137/1019-5149.JTN.49954-25.3
AIM: To investigate corpus callosum shape differences in pediatric hydrocephalus patients with and without shunt revisions.
MATERIAL and METHODS: Midsagittal magnetic resonance imaging studies from 45 cases (25 with and 20 without shunt revision
surgeries) that underwent ventriculoperitoneal shunt...
Case Report
Transnasal Transsphenoidal versus Transcranial Surgery for Resection of Sellar Lesions; A National Database Analysis
Pages: 316-320
DOI: 10.5137/1019-5149.JTN.48023-24.1
AIM: To present a national database analysis comparing transnasal transsphenoidal (TNTS) and transcranial (TC) approaches in
sellar lesion management.
MATERIAL and METHODS: We analyzed the National Surgical Quality Improvement Program (NSQIP) database by TNTS and TC
CPT codes from 2014-2018. Outc...
Systematic Review
Letter to Editor
Evaluation of Drugs with Selective Inhibitors Targeting the Anti-Apoptotic Protein B-cell Lymphoma 2 (BCL-2) with Pro-Apoptotic and Antineoplastic Activities in Grade IV Glioblastoma
Pages: 294-301
DOI: 10.5137/1019-5149.JTN.48543-25.1
AIM: To systemically review the efficacy, safety, and clinical applications of B-cell lymphoma 2 (BCL-2) family inhibitors such as
venetoclax (ABT-199), navitoclax (ABT-263), and obatoclax (GX15-070) across different malignancies.
MATERIAL and METHODS: A systematic search was conducted in the PubM...
Case Report
Pages: 321-326
DOI: 10.5137/1019-5149.JTN.48634-25.1
Spinal meningiomas are common intradural spinal tumors. Recurrent multilevel ventral intradural extramedullary spinal meningiomas,
especially those presenting several years post-initial surgery is rare and can be particularly challenging to treat. We report two cases
of such recurrent multilevel v...
Pages: 327-331
DOI: 10.5137/1019-5149.JTN.47293-24.4
The formation of histologically mature bone within the intracranial compartment is an exceptionally rare phenomenon. Although
intracranial calcifications are frequently encountered in clinical practice, true ossification culminating in the development of mature
bone tissue remains poorly character...
Pages: 332-336
DOI: 10.5137/1019-5149.JTN.48274-24.3
Carotid blowout syndrome (CBS) refers to involvement of the carotid artery by malignant processes of the head and neck with
compromise of vessel integrity and rupture. Carotid hemorrhage (CBS type III) is fatal, particularly when it occurs outside hospital
settings. Bleeding can occur through the ...
Letter to Editor
Pages: 337-338
DOI: 10.5137/1019-5149.JTN.49136-25.2
Pages: 339-339
DOI: 10.5137/1019-5149.JTN.49541-25.3