E-ISSN: 1019-5157
ISSN: 2651-5024
History
Turkish Neuro -Excursion
Review
Pages: 639-645
DOI: 10.5137/1019-5149.JTN.8878-13.1
The aim of this study was to a conduct a systematic review of carmustine wafers (Gliadel wafers) for the treatment of glioblastoma multiforme
(GBM) to assess the survival benefit and safety of this therapy. The inclusion criteria were 1) prospective or retrospective clinical trial; 2) patients
who...
Pages: 646-657
DOI: 10.5137/1019-5149.JTN.8838-13.0
Scoliosis refers to curves exceeding 10 degrees observed through posterioanterior direct radiography. In fact, the diagnosis for idiopathic
scoliosis is accepted to exclude already available causes. The aim of this paper was to review the etiopathogenesis, classification systems
and the treatment ...
Original Investigation
Pages: 658-663
DOI: 10.5137/1019-5149.JTN.8412-13.2
AIM: Most dural arteriovenous fistulas (DAVFs) can be treated safely and effectively with endovascular Onyx embolization. Balloon-assisted
endovascular Onyx embolization of intracranial DAVFs is especially suitable for arterial protection and arterial flow reduction in complicated
DAVFs. We system...
Pages: 664-671
DOI: 10.5137/1019-5149.JTN.7668-13.2
AIM: The aim of this study was to evaluate our treatment and outcome in patients with large medial sphenoid wing meningiomas (SWMs).
MATERIAL and METHODS: Data from 178 patients with large medial SWMs treated was collected and analyzed retrospectively. Most of
patients underwent microsurgical rese...
Pages: 672-678
DOI: 10.5137/1019-5149.JTN.9030-13.2
AIM: Multi-profile monitoring of various blood serum factors during acute subarachnoid haemorrhage (SAH) is crucial for successful treatment.
The aim of the study is to evaluate the serum concentration of different blood factors in the acute period of SAH.
MATERIAL and METHODS: 31 patients with co...
Pages: 679-687
DOI: 10.5137/1019-5149.JTN.9140-13.1
AIM: Pituitary adenomas do not have a single factor of aggressive behavior or recurrence. The objective of this study was to determine factors
influencing the prognosis in pituitary adenomas.
MATERIAL and METHODS: 243 patients who were operated between January 2000 and June 2012 were included in t...
Pages: 688-694
DOI: 10.5137/1019-5149.JTN.9285-13.1
AIM: The authors review their experience in the endoscopic endonasal transsphenoidal treatment of 5 patients, finally diagnosed as primary
hypophysitis but initially assumed to be pituitary adenomas.
MATERIAL and METHODS: A retrospective study was undertaken to review 5 cases of primary non-necrot...
Pages: 695-698
DOI: 10.5137/1019-5149.JTN.9283-13.2
AIM: This work aims to summarize the experience in emergency microsurgery for patients with aneurysmal subarachnoid hemorrhage (SAH)
that coexisted with brain hernia.
MATERIAL and METHODS: A total of 26 patients with aneurysmal SAH complicated by brain hernia were subjected to emergency aneurysm
...
Pages: 699-703
DOI: 10.5137/1019-5149.JTN.9281-13.1
AIM: To compare the effects of post neurosurgical antimicrobial prophylaxis before and after the adoption of a new protocol in our department,
which changed from prolonged prophylaxis to limited usage.
MATERIAL and METHODS: Two cross-sectional studies were performed to compare the 24-hour antimicr...
Pages: 704-709
DOI: 10.5137/1019-5149.JTN.9059-13.1
AIM: Topiramate is an antiepileptic drug with multiple mechanisms of action that is also used for migraine prophylaxis. This study aimed
to investigate the efficacy of topiramate therapy for migraine prophylaxis, based on vasomotor reactivity ([VMR] an indicator of cerebral
autoregulation), and to...
Pages: 710-712
DOI: 10.5137/1019-5149.JTN.9468-13.1
AIM: To investigate the effect of locally administered intracisternal papaverine on the pupils during cerebral aneurysm clipping.
MATERIAL and METHODS: Four patients that received cerebral aneurysm clipping were included in the study. Papaverine (3%, 60 mg) was
dropped into the internal carotid ar...
Pages: 713-719
DOI: 10.5137/1019-5149.JTN.9465-13.0
AIM: This study aimed to evaluate the short- to medium-term outcomes of the second-generation Wallis interspinous dynamic stabilization
device for treatment of lumbar degenerative disease.
MATERIAL and METHODS: Fifty patients with lumbar degenerative disease treated from August 2007 to September 2...
Pages: 720-725
DOI: 10.5137/1019-5149.JTN.9753-13.1
AIM: Surgery for lesions involving the anterior column of the cervicothoracic junction is still challenging. The median transsternal approach
provides a direct approach to this junction. The aim of this study was to present the results of cases operated using the median transsternal
approach.
MAT...
Pages: 726-730
DOI: 10.5137/1019-5149.JTN.9718-13.1
AIM: To improve the strength of stabilization systems currently used in osteoporotic spinal fractures, essentially by increasing the fixation force
of pedicle screws.
MATERIAL and METHODS: Six human cadaveric vertebrae were used. Bone mineral densities of the specimens were measured with Dual
Ene...
Pages: 731-736
DOI: 10.5137/1019-5149.JTN.9823-13.1
AIM: The matrix metalloproteinase (MMP) enzyme family has been shown to be active in tumorigenesis and tumor progression. In this study, we
analyzed the prevalence of a guanine insertion in the MMP-1 gene promoter region in meningiomas and its effect on invasion and prognosis.
MATERIAL and METHODS...
Pages: 737-744
DOI: 10.5137/1019-5149.JTN.9837-13.2
AIM: External ventricular drainage (EVD) and lumbar drainage (LD) are the most widely used procedures for continued bloody cerebrospinal
fluid drainage. Each has his own advantages and disadvantages. Here, we compared complications and clinical outcomes in patients with
World Federation of Neurosu...
Pages: 745-749
DOI: 10.5137/1019-5149.JTN.9852-13.0
AIM: Heat shock proteins (HSP) are an evolutionary conserved family of proteins that serve as molecular chaperones, preventing the formation
of nonspecific protein aggregates and assisting proteins in the acquisition of their native structures. Furthermore, HSPs have anti-apoptotic
properties and ...
Pages: 750-756
DOI: 10.5137/1019-5149.JTN.9814-13.0
AIM: In this study, 31 patients with a diagnosis of Type II odontoid fractures were reported. All patients were treated with anterior transodontoid
screw fixation and clinical outcomes were reported.
MATERIAL and METHODS: In this study, the retrospective clinical analysis of 31 patients with traum...
Pages: 757-762
DOI: 10.5137/1019-5149.JTN.9914-13.1
AIM: Computed tomography perfusion (CTP) has recently been used to identify regions of potential ischemia due to cerebral vasospasm, and
CTP parameters are able to quantitatively evaluate brain parenchymal perfusion. We performed a meta-analysis as an update of a previous
paper published in 2010 a...
Article With VideoClip
Pages: 763-764
DOI: 10.5137/1019-5149.JTN.12603-14.0
In adolescents and young adults, ependymomas are the most common intramedullary tumors in the spinal cord.These tumors arise from
ependymal cell lining the ventricles and spinal canal. The clinical presentation of intramedullary ependymomas are variable and nonspecific.
They usually present with d...
Case Report
Pages: 765-769
DOI: 10.5137/1019-5149.JTN.8057-13.1
Glomeruloid microvascular proliferation (GMP) is a localized proliferation of vascular endothelial cells resembling a renal glomerule. The nature
of cells participating in the formation of these structures remains unclear. While it is a characteristic feature of glioblastoma, it is rarely seen
in ...
Pages: 770-773
DOI: 10.5137/1019-5149.JTN.8899-13.0
The chondroma originated in falx cerebri and dural convexity is very rare, less than 30 cases reported so far. Here, we report a case of 26-yearold
male, with a huge mass at fronto-parietal falx cerebri, who was misdiagnosed as parafalcine meningioma on preoperative MR imaging.
After surgery, the ...
Pages: 774-777
DOI: 10.5137/1019-5149.JTN.9233-13.0
Vascular complications after lumbar discectomy are rarely seen. We present a unique and potentially life-threatening postoperative
complication from this procedure. A 27-year-old man was admitted to our emergency vascular unit 1 day after a lumbar discectomy, during
which a scalpel blade fragmente...
Pages: 778-781
DOI: 10.5137/1019-5149.JTN.9255-13.1
Intracranial pial arteriovenous fistulas (AVFs) associated with multiple aneurysms of the main feeding arteries are very rare cerebrovascular
lesions. We report a unique case of pial AVFs associated with four aneurysms of the feeding anterior cerebral artery (ACA) which presented
as intracerebral ...
Pages: 782-787
DOI: 10.5137/1019-5149.JTN.9237-13.0
Pituitary apoplexy followed by cerebral infarction is rare. In this report, we present a 42-year-old man who had been diagnosed of pituitary
adenoma presented with a sudden onset of unconsciousness, left hemiplegia and right ptosis. Investigations revealed the development of
pituitary apoplexy. Th...
Pages: 788-792
DOI: 10.5137/1019-5149.JTN.9452-13.0
Extracranial meningiomas of the paranasal sinus are the rare tumors of unclear etiology. We report a case of primary extracranial meningioma
arising from the roof of the sphenoid sinus.
A 60-year-old female presented with 5-month history of right visual disturbance. Imaging studies showed a mass i...
Pages: 793-798
DOI: 10.5137/1019-5149.JTN.9388-13.1
We report the case of a 44-year-old man who experienced a fatal and untreatable delayed vasospasm after resection of a recurrent temporal
IV grade primitive neuroectodermal tumor (PNET). The histological analysis demonstrated a rare rhabdoid variant of the tumor with a diffuse
myxoid degeneration;...
Pages: 799-803
DOI: 10.5137/1019-5149.JTN.9535-13.2
Primary leptomeningeal lymphoma is very rare disease that is a subtype of primary central nervous system (CNS) lymphoma. Primary dural
lymphoma is a subentity of primary leptomeningeal lymphoma and arises from the dura mater without systemic disease. A 47-year-old
woman presented with an indolent ...
Pages: 804-813
DOI: 10.5137/1019-5149.JTN.9594-13.1
Three patients with spinal primary diffuse-type tenosynovial giant cell tumor (DTGCT) received surgical treatment in our department between
2002 and 2012. All 3 patients were female and aged 23, 33, and 44 years. The mean time from symptom onset to diagnosis was 17 months
(range, 5–24 months...
Pages: 814-818
DOI: 10.5137/1019-5149.JTN.9775-13.0
A 42-year-old woman presented with right oculomotor, abducens, and trigeminal palsy. Neuroimaging revealed a small lesion in the right
cavernous sinus mimicking meningioma. Because the symptoms gradually worsened, the patient underwent an endoscopic endonasal
transsphenoidal surgery for tumor biop...